The American Thoracic Society, U.S. Centers for Disease Control and Prevention, European Respiratory Society, and Infectious Diseases Society of America jointly sponsored this new practice guideline on the treatment of drug-resistant tuberculosis (DR-TB). The document includes recommendations on the treatment of multidrug-resistant TB (MDR-TB) as well as isoniazid-resistant but rifampin-suscept…
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a long-acting calcium channel blocker, a blocker of the renin-angiotensin system (angiotensin-converting enzyme inhibitor or angiotensin receptor blocker), and a diuretic. The antihypertensive drugs should be administere…
Emerging data suggest that lifestyle habits may affect blood pressure values. In this review, authors examine the more relevant clinical and epidemiological studies about the influence that multiple lifestyle factors play on development of hypertension. They conclude that there is clear evidence that lifestyle changes can have a favorable effect on prevention and treatment of hypertension, with…
Initial studies applying deep brain stimulation (DBS) of the posteromedial hypothalamus (PMH) to patients with pathological aggressiveness have yielded encouraging results. However, the anatomical structures involved in its therapeutic effect have not been precisely identified. The authors’ objective was to describe the long-term outcome in their 7-patient series, and the tractography analysi…
Abdominal pain is common in patients with Gp, both IG and DG. Severe/very severe upper abdominal pain occurred in 34% of Gp patients and associated with other Gp symptoms, somatization, and opiate medication use
Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder of unknown etiology. Although relatively common in children, how this condition affects brain structure and function in a pediatric population remains unclear. Here, we investigate brain changes in adolescents with IBS and healthy controls. Imaging was performed with a Siemens 3 Tesla Trio Tim MRI scanner equipped wit…
Recurrent abdominal pain (RAP) is one of the most common health complaints in both children and adults. Although RAP is considered a functional disorder rather than an organic disease, affected children and their families can still experience anxiety and concerns that can interfere with school, sports, and regular daily activities and lead to frequent attendances at pediatric emergency departme…
During a Head and Neck surgical training camp in Malindi, Kenya, a 25-year-old male with a large mandibular ameloblastoma was evaluated for surgery given persistent growth and deformity secondary to his lesion. The patient underwent oral cavity composite resection and reconstruction with a fibular free flap. On the evening of postoperative day 1, there was concern for venous congestion of the f…
Soft tissue augmentation utilizing filler material has been used since 1893, with the German surgeon Gustov Neuber performing the first documented autologous fat transfer for correction of a facial defect.1 Since that time, numerous filler materials have been used. Today, products used in vocal fold injection include relatively long-lasting solutions including not only autologous fat but als…
A 63-year-old female with a painless progressive enlarging mass on her right parotid region with 1 year of history admitted to our otorhinolaryngology clinic. Physical examination revealed solid, fixed mass approximately 6 cm in size located in the parotid gland. There was no sign of facial nerve involvement. All other examinations of the head and neck including the nasopharynx were normal. Blo…