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Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults
The epidemiologic characteristics of children and young adults with acute kidney injury have been described in single-center and retrospective studies. We conducted a multinational, prospective study involving patients admitted to pediatric intensive care units to define the incremental risk of death and complications associated with severe acute kidney injury.
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Issues of Acute Kidney Injury Staging and Management in Sepsis and Critical I…
Acute kidney injury (AKI) has a high incidence on intensive care units around the world and is a major complication in critically ill patients suffering from sepsis or septic shock. The short- and long-term complications are thereby devastating and impair the quality of life. Especially in terms of AKI staging, the determination of kidney function and the timing of dialytic AKI management outsi…
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Predicting acute kidney injury: current status and future challenges
Acute kidney injury (AKI) is characterized by an acute decline in renal function and is associated to increased mortality rate, hospitalization time, and total health-related costs. The severity of this ‘fearsome’ clinical complication might depend on, or even be worsened by, the late detection of AKI, when the diagnosis is based on the elevation of serum creatinine (SCr). For these reasons…
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Development of a Pediatric Adverse Events Terminology
In 2009, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) established the Pediatric Terminology Harmonization Initiative to establish a core library of terms to facilitate the acquisition and sharing of knowledge between pediatric clinical research, practice, and safety reporting. A coalition of partners established a Pediatric Terminology Adverse Even…
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Evidence-based milestone ages as a framework for developmental surveillance
Developmental surveillance is the process of monitoring child development over time to promote healthy development and to identify possible problems. Standardized developmental screeners have greater sensitivity than milestone-based history taking. Unfortunately, Canadian screening guidelines, to date, are sparse, logistical barriers to implementation have slowed uptake of screening tests and…
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Nebulised N-Acetylcysteine for Unresponsive Bronchial Obstruction in Allergic…
Many chronic lung diseases are characterized by the hypersecretion ofmucus. In these conditions, the administration of mucoactive agents is often indicated as adjuvant therapy. N-acetylcysteine (NAC) is a typical example of amucolytic agent. A retrospective review of patients with pulmonary aspergillosis treated at the National Aspergillosis Centre Manchester,UnitedKingdom,with NAC between Nove…
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A strategy for weight loss based on healthy dietary habits and control of emo…
A sedentary lifestyle and unhealthy eating habits are major causes of a negative energy balance and excess body weight. The lifestyle of the Mediterranean diet eating pattern significantly reduces risk factors for non communicable diseases. Moreover, emotions have a powerful effect on feeding behavior. There is a direct relationship between food choices (type and amount), emotions and increase…
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Diet in the management of weight loss
Obesity is an established risk factor for numerous chronic diseases, and successful treatment will have an important impact on medical resources utilization, health care costs, and patient quality of life. With over 60% of our population being overweight, physicians face a major challenge in assisting patients in the process of weight loss and weight-loss maintenance. Low-calorie diets can lowe…
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The Quality of Breakfast and Healthy Diet in School-aged Adolescents and Thei…
Dietary habits are an important factor in the protection of adolescent health. The quality and frequency of breakfast and the various food groups can a ect the wellbeing of this population group in both the short and long term. Research indicates that there is a range of relevant variables in the study of diet at this stage: following a weight loss diet, body mass index and the practice of phys…
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Successful drug desensitization in patients with delayed-type allergic reacti…
This was a retrospective study. Inclusion criteria were as follows: age >18 years, documented tuberculosis infection, a previous cutaneous allergic reaction to anti-tuberculosis drugs, and having undergone drug desensitization between January 2003 and March 2014. The definition of allergic reaction to anti-tuberculosis drugs included (1) a temporal relationship between drug use and the allergi…
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