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Exercise programmes for ankylosing spondylitis (Review)
Exercise programmes are oPen recommended for managing ankylosing spondylitis (AS), to reduce pain and improve or maintain functional capacity
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The genetic basis of ankylosing spondylitis: new insights into disease pathog…
Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and the disease is characterized by inflammation and ankylosis, mainly at the cartilage–bone interface and enthesis. HLA-B27 has been known to be the major AS-susceptibility gene for more than 40 years. Despite advances made in the past few…
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Case Report: Dengue Hemorrhagic Fever in Children
A female patient came to the Puskesmas with the patient’s child with complaints of fever for 4 days before going to the Puskesmas. The patient began to feel the body shivering 4 days ago and feeling pain throughout the body accompanied by the shivering and not having energy/ feeling weak. At present, patient complains of headaches, joints ache and feeling she just wanted to stay alone. The pa…
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Chymase Level Is a Predictive Biomarker of Dengue Hemorrhagic Fever in Pediat…
Most patients with dengue experience mild disease, dengue fever (DF), while few develop the life-threatening diseases dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). No laboratory tests predict DHF or DSS. We evaluated whether the serum chymase level can predict DHF or DSS in adult and pediatric patients and the influence of preexisting conditions (PECs) on chymase levels
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Predicting the severity of dengue fever in children on admission based on cli…
Dengue fever is a re-emerging viral disease commonly occurring in tropical and subtropical areas. The clinical features and abnormal laboratory test results of dengue infection are similar to those of other febrile illnesses; hence, its accurate and timely diagnosis for providing appropriate treatment is difficult. Delayed diagnosis may be associated with inappropriate treatment and higher risk…
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Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease …
Care models can affect the clinical outcome of patients with rheumatic and musculoskeletal diseases
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Psoriatic Arthritis
Psoriasis is a common skin disease that is associated with multiple coexisting conditions. The most prevalent coexisting condition, psoriatic arthritis, develops in up to 30% of patients with psoriasis and is characterized by diverse clinical features, often resulting in delayed diagnosis and treatment. Initial reports emphasized a benign course in most patients, but it is now recognized that p…
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The Pathogenesis of Rheumatoid Arthritis
Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications, early death, and socioeconomic costs.1 The cause of rheumatoid arthritis is unknown, and the prognosis is guarded. However, advances in understanding the pathogenesis of the disease have fostered the development of new therapeutics, with improved outcomes. The current trea…
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Knee osteoarthritis: pathophysiology and current treatment modalities
For decades, multiple attempts to fully understand knee osteoarthritis pathophysiology and natural history have been attempted. Despite the extensive amount of research regarding this topic, there are still marked controversies. This multifactorial condition gets influenced by local, systemic, and external factors and its progression and/or response to treatments widely varies from patient to p…
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Intrauterine Growth Restriction: Antenatal and Postnatal Aspects
Intrauterine growth restriction (IUGR), a condition that occurs due to various reasons, is an important cause of fetal and neonatal morbidity and mortality. It has been defined as a rate of fetal growth that is less than normal in light of the growth potential of that specific infant. Usually, IUGR and small for gestational age (SGA) are used interchangeably in literature, even though there exi…
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