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Predicting the severity of dengue fever in children on admission based on cli…
Dengue fever is a re-emerging viral disease commonly occurring in tropical and subtropical areas. The clinical features and abnormal laboratory test results of dengue infection are similar to those of other febrile illnesses; hence, its accurate and timely diagnosis for providing appropriate treatment is difficult. Delayed diagnosis may be associated with inappropriate treatment and higher risk…
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Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease …
Care models can affect the clinical outcome of patients with rheumatic and musculoskeletal diseases
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Psoriatic Arthritis
Psoriasis is a common skin disease that is associated with multiple coexisting conditions. The most prevalent coexisting condition, psoriatic arthritis, develops in up to 30% of patients with psoriasis and is characterized by diverse clinical features, often resulting in delayed diagnosis and treatment. Initial reports emphasized a benign course in most patients, but it is now recognized that p…
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The Pathogenesis of Rheumatoid Arthritis
Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications, early death, and socioeconomic costs.1 The cause of rheumatoid arthritis is unknown, and the prognosis is guarded. However, advances in understanding the pathogenesis of the disease have fostered the development of new therapeutics, with improved outcomes. The current trea…
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Knee osteoarthritis: pathophysiology and current treatment modalities
For decades, multiple attempts to fully understand knee osteoarthritis pathophysiology and natural history have been attempted. Despite the extensive amount of research regarding this topic, there are still marked controversies. This multifactorial condition gets influenced by local, systemic, and external factors and its progression and/or response to treatments widely varies from patient to p…
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Intrauterine Growth Restriction: Antenatal and Postnatal Aspects
Intrauterine growth restriction (IUGR), a condition that occurs due to various reasons, is an important cause of fetal and neonatal morbidity and mortality. It has been defined as a rate of fetal growth that is less than normal in light of the growth potential of that specific infant. Usually, IUGR and small for gestational age (SGA) are used interchangeably in literature, even though there exi…
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Intrauterine Growth Restriction: New Insight from the Metabolomic Approach
Recognizing intrauterine growth restriction (IUGR) is a matter of great concern because this condition can significantly afect the newborn’s short- and long-term health. Ever since the first suggestion of the “thrifty phenotype hypothesis” in the last decade of the 20th century, a number of studies have confirmed the association between low birth weight and cardiometabolic syndrome later…
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Predictive factors for intrauterine growth restriction
Reduced fetal growth is seen in about 10% of the pregnancies but only a minority has a pathological background and is known as intrauterine growth restriction or fetal growth restriction (IUGR / FGR). Increased fetal and neonatal mortality and morbidity as well as adult pathologic conditions are often associated to IUGR. Risk factors for IUGR are easy to assess but have poor predictive value.…
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Indikasi dan Kontraindikasi Ventilasi Noninvasif pada Perawatan di Rumah
Dewasa ini penggunaan ventilasi noninvasif semakin berkembang dan membuat penderita merasa lebih nyaman. Perangkat ini menawarkan biaya perawatan yang lebih murah serta waktu perawatan yang lebih singkat dibandingkan dengan ventilasi invasif. Saat ini ventilasi noninvasif banyak digunakan pada pasien rawat inap dengan gagal napas akut maupun kronik pada perawatan di rumah
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Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD.…
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