In 2016, the Transplantation Society of Australia and New Zealand, with the support of the Australian Government Organ and Tissue authority, commissioned a literature review on the topic of infectious disease transmission from deceased donors to recipients of solid organ transplants. The purpose of this review was to synthesize evidence on transmission risks, diagnostic test characteristics,…
Intubation and extubation of ventilated patients are not risk-free procedures in the intensive care unit (ICU) and can be associated with morbidity and mortality. Intubation in the ICU is frequently required in emergency situations for patients with an unstable cardiovascular or respiratory system. Under these circumstances, it is a highrisk procedure with life-threatening complications (20–5…
Extracts of seaweeds, seagrasses and mangroves from the southeast coast of India have been tested in vitro for antiviral activity against Newcastle disease, vaccinia, Semliki Forest, encephalomyocarditis and hepatitis Β viruses. In the primary test, of 73 extracts examined, 43 exhibited antiviral activity (> 50%) against at least any one of the viruses. Only two extracts, leaf of Bruguiera cyl…
Plants continue to be a major source for new chemical entities to develop novel therapeutic agents. Large number of plants has been shown to be active in vitro against a variety of human pathogenic viruses or their near congeners. In several cases the active compounds have been isolated and characterized
Seaweeds, seagrasses, and mangroves were studied for their antiviral activity against Encephalomyocarditis virus (EMCV). Of 73 extracts, 20 showed in virro anti-EMCV activity. Of these 20 extracts, seven were prophylactically and three were therapeutically active. Only two extracts, Cheilosporum spectabile and Rhizophora mucronata, were found to be effective with both in vitro and in vivo assay…
Osteoarthritis is a prevalent chronic disease that impacts quality of life and imposes a heavy economic burden. Despite this there is no confirmed treatment that could prevent progressive destruction of osteoarthritic joints. Mesenchymal stem cells with their regenerative and immunosuppressive properties have emerged as a potential therapy
Exercise programmes are oPen recommended for managing ankylosing spondylitis (AS), to reduce pain and improve or maintain functional capacity
Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and the disease is characterized by inflammation and ankylosis, mainly at the cartilage–bone interface and enthesis. HLA-B27 has been known to be the major AS-susceptibility gene for more than 40 years. Despite advances made in the past few…
A female patient came to the Puskesmas with the patient’s child with complaints of fever for 4 days before going to the Puskesmas. The patient began to feel the body shivering 4 days ago and feeling pain throughout the body accompanied by the shivering and not having energy/ feeling weak. At present, patient complains of headaches, joints ache and feeling she just wanted to stay alone. The pa…
Most patients with dengue experience mild disease, dengue fever (DF), while few develop the life-threatening diseases dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). No laboratory tests predict DHF or DSS. We evaluated whether the serum chymase level can predict DHF or DSS in adult and pediatric patients and the influence of preexisting conditions (PECs) on chymase levels