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Hypokalemic Periodic Paralysis due to Graves Disease
Hypokalemic thyrotoxic periodic paralysis is a potentially life-threatening complication of hyperthyroidism, defined by 3 characteristic features: thyrotoxicosis, hypokalemia, and acute painless muscle weakness. In this case, a 25-year-old Malaysian man presented with acute, painless lower extremity weakness immediately after a meal. His associated symptoms included palpitations, tremor, and a…
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PRACTICE GUIDELINE FOR THE TREATMENT PATIENS WITH HIV/AIDS
Since publication in 2000 of APA’s Practice Guideline for the Treatment of Patients With HIV/ AIDS (1), new evidence has become available that affects the psychiatric care of patients with human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). This guideline watch highlights this evidence for the following areas: epidemiology, antiretroviral medication re…
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Cardiovascular Management in Pregnancy: Congenital Heart Disease
Marked advances in the treatment of congenital heart disease (CHD) have resulted in a growing population of adults with CHD, currently estimated at >1 million adults (at least equal to the pediatric population).1 Many of these are young women, facing decisions about childbearing, and will require expert care. A recent analysis of a large nationally representative hospital discharge database in…
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The role of vitamin D in pre-eclampsia: a systematic review
The etiology of pre-eclampsia (PE) is not yet fully understood, though current literature indicates an upregulation of inflammatory mediators produced by the placenta as a potential causal mechanism. Vitamin D is known to have anti-inflammatory properties and there is evidence of an inverse relationship between dietary calcium intake and the incidence of PE. Evidence of the role of vitamin D s…
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PCOS: update and diagnostic approach
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, commonly diagnosed in reproductive age women. Its estimated prevalence ranges between 5% and 15% [1, 2]. It is often associated with infertility as well as a higher risk of obesity, dyslipidaemia, and detrimental long-term consequences such as type 2 diabetes and cardiovascular disease.
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Clinical risk factors for pre-eclampsia determined in early pregnancy: system…
To develop a practical evidence based list of clinical risk factors that can be assessed by a clinician at ≤16 weeks’ gestation to estimate a woman’s risk of pre-eclampsia
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The association between maternal smoking and placenta abruption: a meta-analysis
Several epidemiological studies have determined that maternal smoking can increase the risk of placenta abruption. To date, only a meta-analysis has been performed for assessing the relationship between smoking and placenta abruption. This meta-analysis was conducted to estimate the association between smoking and the risk of placenta abruption
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Placenta abruption surface and perinatal outcome
This prospective descriptive study was carried out from February 1st to September 30th, 2014. We recruited all women whose delivery was complicated by PA with onset preceded by the presence of active fetal movement. PA surface was assessed by placental examination after delivery. Main outcome measures were gestational age, Apgar score, location and percentage of PA. Data were analyzed using SPS…
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Association of Fenofibrate Therapy With Long-term Cardiovascular Risk in Stat…
Patients with type 2 diabetes are at high risk of cardiovascular disease (CVD) in part owing to hypertriglyceridemia and low high-density lipoprotein cholesterol. It is unknown whether adding triglyceride-lowering treatment to statin reduces this risk.
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The pregnant woman with heart disease: management of pregnancy and delivery
Women with heart disease are at risk of cardiac complications during pregnancy and delivery. Risk assessment should be performed in these women, and the management of pregnancy and delivery should be planned accordingly. Depending on the risk, women should be cared for in specialised centres, regional centres or a combination of both. Multidisciplinary teams must be involved in the care of th…
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