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PATIENTS PREFER SUBCUTANEOUS PROGESTERONE OVER VAGINAL ADMINISTRATION. UNEXPE…
OBJECTIVE: To determine if subcutaneous or transvaginal progesterone are preferred by patients after the use of both, based on the influence on their sexual life, global comfort and interference on their normal activities.
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Water soluble progesterone–hydroxypropyl-b-cyclodextrin complex for injecta…
The use of cyclodextrin to increase the water solubility of progesterone (P) was described by Pitha as a complex with b-cyclodextrin and derivates to obtain a water soluble formulation (Pitha, J.: US patent n. 4,727,064). Hydroxypropyl-b-cyclodextrin (HPBCD) has a high water solubility which allows the solubilization of high quantity of P. Considering a 1:2 guess/host complex stoichiometry it…
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Knowledge Sharing Session : Vaping 101 - All You Need To Know from Head to Toe
Dulu, asap tembakau dipercaya membawa berkah, simbol spiritual, bahkan dianggap menyehatkan. Hingga akhirnya sains berbicara lain. Kini, dua puluh tahun terakhir, muncul babak baru: e-cigarette dan vape. Awalnya diciptakan dengan niat baik yaitu untuk membantu perokok beralih ke pilihan yang lebih “sehat.” Tapi apakah benar tubuh kita menyambutnya dengan lebih baik? Mari kita lihat…
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Intravenous ibuprofen in postoperative pain and fever management in adults: A…
This study aims to evaluate the efficacy and safety of multiple or single-dosage intravenous ibuprofen (IVIB) in managing postoperative pain and fever in adults who are unable to take oral medications. A systematic review and meta-analysis was conducted based on randomized controlled trials (RCTs) comparing IVIB with placebo or other analgesic and antipyretic medications for postoperative pai…
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Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrat…
Ibuprofen first came to market about 50 years ago and rapidly moved to over-thecounter (OTC) sales. In April 2019, the National Agency for the Safety of Medicines and Health Products (ANSM) of France issued a warning for NSAID uses by patients with infectious diseases based on an analysis of 20 years of real-world safety data on ibuprofen and ketoprofen. Nevertheless, ibuprofen remains a mainst…
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Comparative evaluation of the efficacy of intravenous paracetamol and ibuprof…
Tonsillopharyngitis is one of the constituents of upper respiratory tract infection (URTI). Fever is a URTI symptom requiring treatment due to the occurrence of discomfort and high fever‑based complications. This study primarily sets out to observe and compare the efficacy of intravenous administration of paracetamol and ibuprofen drugs on fever in adult patients with tonsillopharyngitis
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Comparison of Intravenous Ibuprofen Versus Intravenous Ketorolac in Acute Pos…
Non-steroidal anti-inflammatory drugs (NSAIDs) are popularly used in the management of acute postoperative pain. Intravenous (IV) ketorolac has been used for several years for this purpose. Recently, IV ibuprofen has been introduced for the management of postoperative pain. This review aims to compare the efficacy of these two NSAIDs in managing acute postoperative pain. After registering the p…
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A multi-center, randomized, double-blind, parallel, placebo-controlled trial …
Hospitalized patients are often unable to ingest or tolerate oral antipyretics and recently an aqueous formulation of intravenous (IV) ibuprofen was approved by the US-FDA for the reduction of fever in adults.
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Prospective evaluation of the emetogenic profile and analgesic efficacy of in…
In our cohort, ibuprofen had a similar analgesic efficacy and a better emetogenic profile than metamizole in the immediate postoperative period of PAA. Future prospective, adequately controlled studies with larger sample sizes are needed to validate these findings.
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Effect of single dose preoperative intravenous ibuprofen on postoperative pai…
Ibuprofen, a well-known analgesic, is commonly used as a component of a multimodal analgesic approach for postoperative pain. This systematic review and meta- analysis aimed to investigate whether a single-dose preoperative intravenous ibuprofen can reduce postoperative pain and opioid consumption
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