Efficacy and safety of rituximab combined with chemotherapy in the treatment …

The aim of this study is to systematically evaluate the safety and efficacy of rituximab plus CHOP (R-CHOP combined regimen) in patients with previously untreated diffuse large B cell lymphoma (DLBCL). Electronic database were searched for randomized-controlled studies only comparing R-CHOP to CHOP standard alone in patients with untreated DLBCL were included. The risk ratios (RRs) with their 9…

Radiotherapy plus rituximab as first-line regimen for localized follicular ly…

Early-stage follicular lymphoma (FL) can be cured with involved-field radiotherapy (IF-RT); however, many patients relapse in non-irradiated areas. A combined association with chemotherapy could increase treatment efficacy, but toxic effects could be unacceptable. In vitro synergistic effect between rituximab (R) and RT has been observed, but clinical data are limited. We retrospectively analyz…

Rituximab as First-Line and Maintenance Therapy for Patients With Indolent No…

To evaluate response to single-agent rituximab in patients with indolent non-Hodgkin’s lymphoma (NHL) and no previous systemic therapy, and the feasibility, toxicity, and efficacy of maintenance rituximab, administered at 6-month intervals, in patients with objective response or stable disease after first-line rituximab therapy.

Rituximab monotherapy with eight weekly infusions for relapsed or refractory …

Information regarding rituximab monotherapy with eight weekly infusions for relapsed or refractory indolent B cell non-Hodgkin lymphoma (B-NHL), in particular for patients pretreated with rituximab, is limited. To evaluate the efficacy and safety of eight doses of rituximab monotherapy, 52 patients with relapsed or refractory indolent B-NHL were enrolled in the present study. Forty of 45 eligib…

The Use and Effectiveness of Rituximab Maintenance in Patients with Follicula…

A total of 1439 patients completed R-based induction therapy, 1186 of whom met all inclusion criteria (541 patients received R-maintenance and 645 patients were observed). Characteristics that were found to be predictive of receiving R-maintenance were histology grade (1/2), Ann Arbor stage of disease (III/IV), geographic region (region other than the West), and practice setting (community prac…

Nebulized Salbutamol Vs Salbutamol and Ipratropium Combination in Asthma

To see the additional benefit of combined frequent nebulization with salbutamol and ipratropium bromide in acute attack of asthma with moderate severity

Efficacy and safety of ipratropium bromide/ albuterol compared with albuterol…

Many patients with asthma require frequent rescue medication for acute symptoms despite appropriate controller therapies. Thus, determining the most effective relief regimen is important in the management of more severe asthma. This study’s objective was to evaluate whether ipratropium bromide/albuterol metered-dose inhaler (CVT-MDI) provides more effective acute relief of bronchospasm in mod…

Comparison of clinical efficacy and safety between salbutamol-ipratropium bro…

Indonesian guidelines for childhood asthma recommend giving ipratropium bromide when there are no improvement after 2 times salbutamol nebulization. The efficacy and safety of early nebulization of ipratropium bromide combined with salbutamol as first line in moderate asthma exacerbation in children are still unknown

N-acetylcysteine inhibit biofilms produced by Pseudomonas aeruginosa

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Effects of N-acetylcysteine on Semen Parameters and Oxidative/Antioxidant Status

To examine whether a beneficial effect of N-acetylcysteine (NAC) on semen parameters and oxidative/antioxidant status in idiopathic male infertility exists. The production of reactive oxygen species is a normal physiologic event in various organs. However, overproduction of reactive oxygen species can be detrimental to sperm and has been associated with male infertility