A Review of Micronutrients and the Immune System–Working in Harmony to Redu…

Immune support by micronutrients is historically based on vitamin C deficiency and supplementation in scurvy in early times. It has since been established that the complex, integrated immune system needs multiple specific micronutrients, including vitamins A, D, C, E, B6, and B12, folate, zinc, iron, copper, and selenium, which play vital, often synergistic roles at every stage of the immune re…

Effects of the angiotensin-receptor blocker telmisartan on cardiovascular eve…

Angiotensin-converting enzyme (ACE) inhibitors reduce major cardiovascular events, but are not tolerated by about 20% of patients. We therefore assessed whether the angiotensin-receptor blocker telmisartan would be eff ective in patients intolerant to ACE inhibitors with cardiovascular disease or diabetes with end-organ damage.

Antimicrobial actvity of 1% Feracrylum

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Hydroxy Acids and Retinoids in Cosmetics

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Cisapride : An Updated Review of its Pharmacology and Therapeutic Efficacy a…

Cisapride is an orally administered prokinetic agent which facilitates or restores motility throughout the length of the gastrointestinal tract. It is a substituted piperidinyl benzamide, chemically related to metoclopramide, but unlike metoclopramide, cisapride is largely devoid of central depressant or antidopaminergic effects. In placebo-controlled trials, cisapride improved healing rates an…

Cisapride: A Novel Gastroprokinetic Drug

Impaired gastrointestinal motility underlies a multitude of digestive complaints. Metoclopramide, an antidopaminergic and cholinomimetic agen~ was the first prokinetic drug used to treat such conditions, but a high incidence of adverse effects has limited its use, especially in inf ants. Domperidone, the second prokinetic drug marketed in Canada, is a potent peripheral dopamine receptor antagon…

Cisapride Improves Enteral Tolerance in Pediatric Short Bowel Syndrome with D…

Gastrointestinal (GI) dysmotility is common in pediatric short bowel syndrome (SBS), leading to prolonged parenteral nutrition (PN) dependence. There is limited literature regarding the safety and efficacy of cisapride for this indication

Functional Dyspepsia

Dyspepsia is a constellation of symptoms referable to the gastroduodenal region of the upper gastrointestinal tract. Functional dyspepsia, a relapsing and remitting disorder, is the most common cause of these symptoms. The current standard for the diagnosis of functional dyspepsia is the Rome III criteria, developed by the Rome III Committees, a multinational group of experts in the field, firs…

Pharmacokinetic Profile of Cisapride 20 mg After Once- and Twice-Daily Dosing

Cisapride is a substituted piperidinyl benzamide. It is chemically related to metoclopramide but lacks the antidopaminergic properties of metoclopramide that affect the central nervous system and cause extrapyramidal side effects. Cisapride is indicated for the symptomatic treatment of patients with nocturnal heartburn due to gastroesophageal reflux disease. Based on extensive assessment of t…

Nun-ulcer dyspepsia ; myths and realities

Dyspepsia can be defined as the presence of upper abdominal pain or discomfort; other symptoms referable to the proximal gastrointestinal tract, such as nausea, early satiety, and bloating, may also be present. Symptoms may or may not be meal related. To be termed chronic, dyspepsia should have been present for three months or longer. Over half the patients who present with chronic dyspepsia ha…