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Combination Nasal Steroid-Antihistamine Is More Effective Than Either Agent A…
Intranasal steroids are the most effective pharmacologic treatment for seasonal allergic rhinitis (SAR), but they can take several days to take effect, and some patients don't achieve full relief of symptoms. Add-on oral antihistamines or montelukast (Singulair) do not add much benefit.
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Tsunami lung
We encountered three cases of lung disorders caused by drowning in the recent large tsunami that struck following the Great East Japan Earthquake. All three were females, and two of them were old elderly.
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Wound healing
Wound healing is an important physiological process to maintain the integrity of skin after trauma, either by accident or by intent procedure. The normal wound healing involves three successive but overlapping phases, including hemostasis/inflammatory phase, proliferative phase, and remodeling phase. Aberration of wound healing, such as excessive wound healing (hypertrophic scar and keloid) o…
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GYNECOLOGY: Variation in Gynecologic Aseptic Technique
There are limited data available regarding the optimal protocol for preoperative skin asepsis and the steps of intraoperative patient preparation including draping, Foley, and uterine manipulator placement. Given the lack of a standard process, it is anticipated that these steps are performed in a variety of sequences
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Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) in which the immune system damages the protective insulation surrounding the nerve fibers that project from neurons. A hallmark of MS and its animal model, experimental autoimmune encephalomyelitis (EAE), is autoimmunity against proteins of the myelin sheath. Most studies in this field have focused …
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Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema
Triamcinolone acetonide injectable suspension for suprachoroidal use (Xipere ® ; SCS triamcinolone acetonide) is a cor- ticosteroid approved in the USA for the treatment of macular edema associated with uveitis. Suprachoroidal injection of SCS triamcinolone acetonide results in preferential distribution into the posterior segment, which may reduce the risk of corticosteroid-related adverse …
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Safety and Systemic Exposure of Triamcinolone Acetonide Following Ultrasoundâ…
Osteoarthritis (OA) is a major public health burden. While knee and hip joints are most com- monly affected, the glenohumoral (shoulder) joint is also frequently involved. We evaluated the pharmacokinetics and safety/ tolerability of triamcinolone acetonide extended-release (TA-ER) and triamcinolone acetonide crystalline suspension (TAcs) in patients with shoulder OA.
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Efficacy of different routes of triamcinolone acetonide administration on mac…
There is different administration routes of triamcinolone acetonide (TA) administration for macular edema, but the efficacy ranking remains unclear. The purpose of this study is to assess the efficacy of different administration routes of TA employed in macular edema. PubMed, Medline, Embase, and Cochrane Central Register of Controlled Trials were systematically searched for published articles…
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Comparison of fluoroquinolones: cytotoxicity on human corneal epithelial cells
To compare the cytotoxicity of different fluoroquinolones (FQs) towards human corneal epithelial cells (HCECs).
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Meta-analysis on Effectiveness and Safety of Moxifloxacin in Treatment of Mul…
Moxifloxacin, a fourth generation fluoroquinolone, which has good antibacterial activity against both Gram-positive cocci and Gram-negative bacteria. To date, there are no meta-analysis to evaluate the efficacy and safety of moxifloxacin for multidrug resistant tuberculosis (MDR-TB) treatment. This meta-analysis to explore the efficacy and safety of the moxifloxacin in treatment of MDR-TB in ad…
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