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Acute Bronchial Asthma
Acute asthma is the third commonest cause of pediatric emergency visits at PGIMER. Typically, it presents with acute onset respiratory distress and wheeze in a patient with past or family history of similar episodes. The severity of the acute episode of asthma is judged clinically and categorized asmild, moderate and severe. The initial therapy consists of oxygen, inhaled beta-2 agonists (salbu…
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The Role of Budesonide in Adults and Children with Mild-to-Moderate Persisten…
Asthma, a chronic and potentially life-threatening disease of the airways, affects patients of all ages. Inhaled corticosteroids (ICS) are the recommended first-line therapy for patients with persistent asthma. To review the clinical efficacy and tolerability data available on budesonide in the treatment of mild-to-moderate persistent asthma, a MEDLINE database search was performed for 1996–2…
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Efficacy of Budesonide in Moderate to Severe Asthma
The worldwide prevalence of asthma is increasing by -50% per decade. Budesonide is one of several inhaled corticosteroids available for the treatment of asthma and has been extensively evaluated in clinical trials
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Inhaled budesonide in the management of acute worsenings and exacerbations of…
The use of systemic corticosteroids, together with bronchodilators and oxygen therapy, has become established for the management of acute asthma. These agents are undoubtedly effective, but are also associated with problems such as metabolic adverse effects. Inhaled corticosteroids (ICS) offer potential benefit in the acute setting because they are delivered directly to the airways. They are al…
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A Review on the Safety and Efficacy of Inhaled Corticosteroids in the Managem…
Asthma is a chronic inflammatory disease characterized by symptoms of cough, dyspnea, chest tightness, and wheeze. Inhaled corticosteroids (ICS) have been recommended as initial therapy in the treatment of persistent asthma in all guidelines, as they have been shown to reduce morbidity and mortality
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Short-term and long-term safety of budesonide inhalation suspension in infant…
This article reviews the short-term and long-term safety profile of budesonide inhalation suspension (BIS) for nebulization in infants and young children with persistent asthma.
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The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) stud…
The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) study enrolled 7241 patients aged 5 to 66 years with recent-onset, mild persistent asthma to assess early intervention with the inhaled corticosteroid budesonide on long-term asthma control.
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Budesonide Inhalation Suspension for the Treatment of Asthma in Infants and C…
On the basis of the well recognised role of inflammation in the pathogenesis of asthma, anti-inflammatory therapy, in the form of inhaled corticosteroids, has become the mainstay of treatment in patients with persistent asthma. Budesonide inhalation suspension (BIS) is a nonhalogenated corticosteroid with a high ratio of local anti-inflammatory activity to systemic activity
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Role of local instillation of one percent feracrylum and haemocogulase on wou…
The introduction of increasingly complex and major surgical procedures during the last 50 years has inevitably been accompanied by greater problems in wound healing. Fortunately, modern surgery is relatively safe, certainly by comparison with situation 50 years ago, but it cannot be said that it is totally devoid of risks or complications, and problems of wound healing are encountered in every …
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Update on Molecular Testing for Cytologically Indeterminate Thyroid Nodules
Fine needle aspiration biopsy (FNAB) and ultrasonography are the most common modalities for the diagnosis and follow up of thyroid nodules. FNAB is able to distinguish benign from malignant nodules with high sensitivity and specificity; however, 20% to 30% of nodules are diagnosed as indeterminate with a risk of malignancy varying from 10% to 75% based on the 2017 revision of the Bethesda Syst…
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