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Tuberculous meningitis: advances in diagnosis and treatment
Tuberculous meningitis (TBM) is the most severe form of infection caused by Mycobacterium tuberculosis, causing death or disability in more than half of those affected. The aim of this review is to examine recent advances in our understanding of TBM, focussing on the diagnosis and treatment of this devastating condition.
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Tuberculous meningitis: Diagnostic and therapeutic challenges
Neurologists are often the first medical providers to evaluate patients with possible infectious meningitis. Knowledge of the clinical presentations and cerebrospinal fluid, microbiologic, and neuroimaging findings for different etiologies is essential to make a prompt diagnosis and initiate appropriate treatment
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Murine model of TB meningitis
Central nervous system (CNS) infections caused by Mycobacterium tuberculosis (MTB) are the most severe forms of extrapulmonary TB (EPTB) due to high levels of mortality and neurological morbidity. Limited studies are available on CNS-TB animal-model development, despite the steady rise in cerebral-TB cases in India over the past decade. This study describes the development of a murine model…
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Cerebrospinal Fluid in Critical Illness
To detail the physiology, pathophysiology and recent advances in diagnostic analysis of cerebrospinal fluid (CSF) in critical illness, and briefly review the pharmacokinetics and pharmaco-dynamics of drugs in the CSF when administered by the intravenous and intrathecal route.
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Prevention of decompensation in cirrhosis: a new youth for β blockers
The natural history of cirrhosis can be described as a continuum from a compensated phase to decompensation and liver failure, marked by the development of ascites, overt hepatic encephalopathy, or variceal haemorrhage, occurring at a rate of 5–7% per year.
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Analysis of IL-6, IL-10, IL-17 levels in the blood of patients with chronic h…
To investigate the role and significance of serum IL-6, IL-10, IL-17 in the occurrence and development of chronic hepatitis B. Methods: Enzyme-linked immunosorbent assay (ELISA) was used to detect serum IL-6, IL-10, IL-17 levels and liver function in patients with hepatitis B and relationship between serum viral load in 70 cases of CHB patients and 20 healthy subjects (control group)
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DIAGNOSIS AND TREATMENT OF PSYCHOSOMATIC GASTRITIS AT A PRIMARY HEALTH CLINIC…
Indonesia memiliki jumlah penduduk yang sangat banyak, yaitu 238.452.952 jiwa. Dari jumlah populasi tersebut, terdapat 274.396 kasus gastritis. Namun, psikosomatis gastritis hanya dilaporkan dari sangat sedikit pasien. Karena kasus gastritis banyak di Indonesia dan dengan berjalannya BPJS kesehatan, maka pelayanan kesehatan primer harus melakukan diagnosa dan menangani kasus tersebut. Studi ini…
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Randomized Clinical Trial of Intramuscular vs Oral Methylprednisolone in the …
To compare the efficacy of long-acting IM methylprednisolone to tapering oral methylprednisolone in adult asthmatic patients discharged from the emergency department (ED).
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Injection with methylprednisolone proximal to the carpal tunnel: randomised d…
To assess the effect of a 40 mg methylprednisolone injection proximal to the carpal tunnel in patients with the carpal tunnel syndrome
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A Randomized comparison of 100-mg vs 500-mg dose of methylprednisolone in the…
There have been conflicting reports comparing the effects of various doses of corticosteroids in the treatment of acute asthma. The purpose of this study was to compare 100 mg with 500 mg of methylprednisolone in the emergency department treatment of acute asthma. We studied 150 patients presenting to the emergency department with acute asthma.
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