Comparison of Topical Hemostatic Agents in Elective Hepatic Resection: A Clin…

To compare the difference in efficacy of microcrystalline collagen powder (CL) and fibrin glue (FG) in elective hepatic resection, 62 patients (female 14, male 48) with ages ranging from 51 to 75 years were randomly allocated to receive either CL or FG as a topical agent during hepatectomy. There were no significant differences between the patients treated with CL (n = 31) and those treated wit…

The Importance of Factor XIII as a Component of Fibrin Sealants

The need for factor XIII (FXIII) in fibrin sealant is subject to discussions. Some commercially available fibrin sealants (FS) contain high levels of FXIII (up to 70–80 U/mL) while others contain low levels or none. The objective of the present studies was to investigate the need for FXIII in FS

Fibrin Sealant : A Review of its Use in Surgery and Endoscopy

Fibrin sealant (fibrin adhesive; fibrin glue; Beriplast? P1) is a haemostatic andrnwound support product consisting of the blood coagulation factors fibrinogen,rnfactor XIII and thrombin, the antifibrinolytic agent aprotinin and calcium chloride

Reduction of Post-operative Bleeding after Transurethral Resection of the Pro…

method for instilling a two-component fib'rin adhesive into the prostatic cavity after transurethral resection of the prostate is described. In a prospective, controlled study, 30 consecutive patients undergoing transurethral prostatectomy (TURF') were randomised either to receive treatment with the local instillation of fibrin adhesive into the prostatic cavity or to a control grouprnthat rece…

Prevention of Suture Hole Bleeding Using Fibrin Sealant: Benefits of Factor XIII

Suture hole bleeding is a frequent complicationrnin vascular surgery. The use of fibrin sealantsrn(FSs) during surgery is reported to reduce bloodrnloss by enhancing hemostasis.

Comparison of entecavir and adefovir for the treatment of chronic hepatitis B

The results of several new clinical trials that compared the effectiveness of entecavir (ETV) treatment with that of adefovir (ADV) treatment in patients with chronic hepatitis B (CHB) were published in recent years. However, the numbers of patients included in these clinical trials were too small to draw a clear conclusion as to whether ETV is more effective than ADV. Therefore, a new meta-ana…

Effects of the Disaccharidase Inhibitor Acarbose on Meal and Intravenous Gluc…

To determine whether the effects of the disaccharidase inhibitor Acarbose on glucose tolerance could be solely explained via an action on intestinal nutrient absorption, the effects of this agent and placebo (100 mg p.0.) on intravenous and postprandial glucose tolerance were compared in six normal subjects. Acarbose significantly diminished plasma glucose, insulin, and astrointestinal inhibit…

Glucose Tolerance: The STOP-NIDDM Trial Disease and Hypertension in Patients …

Three hundred forty-one patients (24%) discontinued their participation prematurely, 211 in the acarbose-treated group and 130 in the placebo group; these patients were also followed up for outcome parameters. Decreasing postprandial hyperglycemia with acarbose was associated with a 49% relative risk reduction in the development of cardiovascular events (hazard ratio [HR], 0.51; 95% confidence …

Treatment of Severe Diphtheritic Myocarditis by Temporary Insertion of a Card…

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The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy

Myocarditis is a diverse group of heart-specific immune processes classified by clinical and histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with inflammation or viral infection. Recent experimental studies revealed complex regulatory roles for several microribonucleic acids and T-cell and macrophage subtypes.