To address compliance with oral antidiabetic agents and its impact on metabolic control in type 2 diabetic patients treated in general practice.
Metformin, a biguanide antihyperglycemic medication, lowers blood glucose in patients with type 2 diabetes with minimal risk of hypoglycemia. Most common side effects include diarrhea, nausea and vomiting. Extended-release metformin (Glucophage XR)*, a once-daily tablet using the patented GelShield Diffusion System release mechanism, may be better tolerated than immediate-release metformin (Glu…
The efficacy, dose–response relationships and safety of an extended-release formulation of metformin (Glucophage1 XR) were evaluated in two double-blind, randomized, placebo-controlled studies of 24 and 16 weeks’ duration, in patients with inadequate glycaemic control despite diet and exercise. Protocol 1 provided an evaluation of metformin XR at a commonly used dosage. Protocol 2 evalua…
Your doctor has determined that you have radiation colitis, an inflammation of the colon that occurs as a side effect of cancer radiation therapy to the abdomen or pelvis. The condition can arise from external radiation treatment delivered by a high energy X-ray machine or internal radiation therapy, which is delivered through small implants placed directly into or near the cancerous tumor
Ovarian cancer is predominantly a disease of older, postmenopausal women with the majority (>80%) of cases being diagnosed in women over 50 years.
Primary lung cancer is the most common malignancy after nonmelanocytic skin cancer with deaths from lung cancer exceeding those from any other type of malignancy worldwide
Docosahexaenoic acid (DHA) supplementation during pregnancy has been recommended by several health organizations due to its role in neural, visual, and cognitive development. There are several fat sources available on the market for the manufacture of these dietary supplements with DHA. These fat sources differ in the lipid structure in which DHA is esterified, mainly phospholipids (PL) and tri…
Dietary fat intake in pregnancy and lactation affects pregnancy outcomes and child growth, development and health. The European Commission charged the research project PERILIP, jointly with the Early Nutrition Programming Project, to develop recommendations on dietary fat intake in pregnancy and lactation. Literature reviews were performed and a consensus conference held with international expe…
Dietary components are essential for the structural and functional development of the brain. Among these, docosahexaenoic acid, 22:6n-3 (DHA), is critically necessary for the structure and development of the growing fetal brain in utero. DHA is the major n-3 long-chain polyunsaturated fatty acid in brain gray matter representing about 15% of all fatty acids in the human frontal cortex. DHA affe…
Mental health illness associated with poor nutrition is a serious public concern world- wide. The most at risk individuals are children and adolescents in the developing world. Deficiencies in omega-3 DHA fatty acids have long been recognized as a major contribut- ing factor for mental health illnesses. Provision of products rich in omega-3 DHA could address this problem. But most commonly used…