Filter by
Early initiation of eptifibatide in the emergency department before primary p…
A strategy of early initiation of eptifibatide in the ED before primary PCI for STEMI yields superior pre-PCI TIMI frame counts, reflecting epicardial flow, and superior TIMI myocardial perfusion compared with a strategy of initiating eptifibatide in the CCL without an increase in bleeding risk
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Fondaparinux in Acute Coronary Syndromes
Anticoagulant therapy is a major component in the management of acute coronary syndromes (ACS). Anticoagulant-associated adverse events like heparin-induced thrombocytopenia, bleeding complications and need of close monitoring of anticoagulation led to focus on developing agents causing anticoagulation without affecting primary haemostasis. Fondaparinux, a new-age synthetic anticoagulant, acts…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
The use of fondaparinux in pregnancy
Venous thromboembolism (VTE) remains a major cause of morbidity and mortality in pregnancy. Although relatively safe, hypersensitivity reactions to low-molecular weight heparins (LMWHs) are frequently seen in pregnant women, with a reported 20% incidence in this cohort (Bank et al, 2003; Schindewolf et al, 2013). Fondaparinux is a synthetic pentasaccharide that has been extensively studied in…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Comparison of Fondaparinux and Enoxaparin in Acute Coronary Syndromes
The combined use of anticoagulants, antiplatelet agents, and invasive coronary procedures reduces ischemic coronary events but also increases bleeding in patients with acute coronary syndromes. We therefore assessed whether fondaparinux would preserve the anti-ischemic benefits of enoxaparin while reducing bleeding
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Anticoagulants: A Review of the Pharmacology, Dosing, and Complications
Anticoagulants remain the primary strategy for the prevention and treatment of thrombosis. Unfractionated heparin, low molecular weight heparin, fondaparinux, and warfarin have been studied and employed extensively with direct thrombin inhibitors typically reserved for patients with complications or those requiring intervention. Novel oral anticoagulants have emerged from clinical development a…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Bioavailability of fondaparinux to critically ill patients
Venous thromboembolism is a common problem in the intensive care unit (ICU). To decrease its incidence, prophylactic pharmacologic interventions are part of the ICU routine. However, common ICU conditions may impair the bioavailability of subcutaneously administered agents. The present study evaluates the bioavailability of prophylactic subcutaneous fondaparinux to critically ill patients
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
THE ANTIPHOSPHOLIPID SYNDROME
The first antiphospholipid antibody, a complementfixing antibody that reacted with extracts from bovine hearts, was detected in patients with syphilis in 1906. The relevant antigen was later identified as cardiolipin, a mitochondrial phospholipid. This observation became the basis for the Venereal Disease Research Laboratory (VDRL) test for syphilis that is currently used. Mass screening of bl…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Fondaparinux: A Pharmacoeconomic Review of its Use in the Management of Non-…
In OASIS-5, a large pivotal trial in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), subcutaneous fondaparinux 2.5 mg once daily was noninferior to subcutaneous enoxaparin 1mg/kg twice daily (both agents were administered over a mean of about 5 days in combination with antiplatelet therapy) in reducing death or ischaemic events at 9 days, and the efficacy was maintain…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Use of fondaparinux in a patient with antiphospholipid antibody syndrome and …
The diagnosis of antiphospholipid antibody syndrome (APS) requires one or more vascular thromboses in a patient with antiphospholipid antibodies or lupus anticoagulants detected in the blood on at least two occasions 6 weeks apart
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Efficacy and safety of fondaparinux for the prevention of venous thromboembol…
To determine the efficacy and safety of the anticoagulant fondaparinux in older acute medical inpatients at moderate to high risk of venous thromboembolism
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Computer Science, Information & General Works 
Philosophy & Psychology 
Religion 
Social Sciences 
Language 
Pure Science 
Applied Sciences 
Art & Recreation 
Literature 
History & Geography