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ESC Guidelines for the management of acute myocardial infarction in patients …
Guidelines summarize and evaluate all available evidence—at the time of the writing process—on a particular issue, with the aim of assisting physicians in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk–benefit ratio of particular diagnostic or therapeutic means
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Relationship of treatment delays and mortality in patients undergoing fibrino…
Treatment delays may result in different clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) who receive fibrinolytic therapy vs primary percutaneous coronary intervention (PCI). The aim of this analysis was to examine how treatment delays relate to 6-month mortality in reperfusion-treated patients enrolled in the Global Registry of Acute Coronary Events (GRACE)
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An international randomized trial comparing four thrombolytic strategies for …
The relative efficacy of streptokinase and tissue plasminogen activator and the roles of intravenous as compared with subcutaneous heparin as adjunctive therapy in acute myocardial infarction are unresolved questions. The current trial was designed to compare new, aggressive thrombolytic strategies with standard thrombolytic regimens in the treatment of acute myocardial infarction. Our hypothes…
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Emerging and Neglected Infectious Diseases: Insights, Advances, and Challenges
Infectious diseases are a significant burden on public health and economic stability of societies all over the world. They have for centuries been among the leading causes of death and disability and presented growing challenges to health security and human progress.The threat posed by infectious diseases is further deepened by the continued emergence of new, unrecognized, and old infectious d…
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One Health, emerging infectious diseases and wildlife: two decades of progress?
Infectious diseases affect people, domestic animals and wildlife alike, with many pathogens being able to infect multiple species. Fifty years ago, following the wide-scale manufacture and use of antibiotics and vaccines, it seemed that the battle against infections was being won for the human population. Since then, however, and in addition to increasing antimicrobial resistance among bacteri…
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Metal-Based Nanoparticles for the Treatment of Infectious Diseases
Infectious diseases can be transmitted and they cause a significant burden on public health globally. They are the greatest world killers and it is estimated that they are responsible for the demise of over 17 million people annually. The impact of these diseases is greater in the developing countries. People with compromised immune systems and children are the most affected. Infectious disease…
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Energy deficit increases hepcidin and exacerbates declines in dietary iron ab…
Strenuous physical activity promotes inflammation and depletes muscle glycogen, which may increase the iron regulatory hormone hepcidin. Hepcidin reduces dietary iron absorption and may contribute to declines in iron status frequently observed following strenuous physical activity
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ORAL SUPPLEMENTATION WITH FERROUS SULFATE BUT NOT WITH NONIONIC IRON POLYMALT…
Iron deficiency anemia is customarily treated by iron supplementation. However, iron can act as a catalyst of lipid peroxidation in vitro, and high intake of heme iron has been associated with an increased risk of myocardial infarction in some, but not in all epidemiologic studies. We carried out a 6-month trial of the effects of supplementation of men (n=48) with low iron stores with ferrous …
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Effectiveness and strategies of iron supplementation during pregnancy
Iron deficiency continues to be one of the most prevalent single-nutrient deficiencies in the world. Interventions are often designed to prevent the decrease in hemoglobin concentration and the decline in iron stores associated with pregnancy. Although this is believed to be desirable for both the health of the mother and the well-being of the growing fetus, some scientists disagree.
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Review of Studies on the Effect of Iron Deficiency on Cognitive Development i…
Studies on the effect of iron deficiency on children’s cognition and behavior are selectively reviewed, looking for evidence of a causal relationship. Most correlational studies have found associations between irondeficiency anemia and poor cognitive and motor development and behavioral problems. Longitudinal studies consistently indicate that children anemic in infancy continue to have poore…
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