Hyaluronic acid-carboxymethylcellulose reduced postoperative bowel adhesions …

This randomized study demonstrated that hyaluronic acid-carboxymethylcellulose treatment resulted in a reduction in bowel adhesion to the abdominal wall after laparoscopic pelvic surgery and had good clinical safety

Early Experience with Hyaluronic Acid Instillation to Assist with Visual Inte…

The clinical usefulness of hyaluronic acid (HA) instillation during visual internal urethrotomy (VIU) for decreasing the incidence of recurrent urethral stricture was assessed.

Safety and Efficacy of Gliclazide as Treatment for Type 2 Diabetes: A Systema…

Gliclazide has been associated with a low risk of hypoglycemic episodes and beneficial long-term cardiovascular safety in observational cohorts. The aim of this study was to assess in a systematic review and meta-analysis of randomized controlled trials the safety and efficacy of gliclazide compared to other oral glucose-lowering agents (PROSPERO2013:CRD42013004156)

Efectiveness of gliclazide MR 60 mg in the management of type 2 diabetes: ana…

Although the number of antihyperglycemic agents has expanded signifcantly, sulfonylureas (in particular gliclazide) remain an important option because of a variety of patient and health system factors. The large, real world, observational, and international EASYDia trial evaluated the efectiveness of gliclazide modifed release (MR) 60 mg in individuals with type 2 diabetes with a broad range of…

The Effect of In Vitro Hemodilution with Gelatin, Dextran, Hydroxyethyl Starc…

To determine the effects of progressive in vitro hemodilution with various plasma substitutes on whole blood coagulation, blood was obtained from six healthy volunteers. The Thrombelastograph® (TEG; Haemoscope Corp., Morton Grove, IL) variables of reaction time, coagulation time, maximum amplitude, and growth angle were determined. The following plasma substitutes were tested: two gelatin solu…

3.5% urea-linked gelatin is as effective as 6% HES 200/0.5 for volume managem…

To compare the efficacy of volume expansion with 3.5% gelatin and 6% hydroxyethyl starch 200/0.5 in patients undergoing cardiac surgery. The second objective was to compare the two colloids in terms of blood losses and allogeneic blood transfusion exposure rate.

Effects of hydroxyethystarch and gelatin on renal function in severe sepsis: …

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An Open Pilot Study of The Efficacy and Safety of Polygeline in Adult Subject…

There were 43 subjects who completely participated in this study and included in analysis. From baseline levels, haematocrite decreased in first 6 hours during fluid treatment. This decrement persisted in 48 hours of observation. Statistical analysis with ANOVA test showed the significant differences of haematocrite level during observation (Sum of square between groups 495 and within group 484…

Evidence-based Colloid Use in the Critically Ill: American Thoracic Society C…

Critical care clinicians have the opportunity to choose among several intravenous solutions for fluid replacement. These fall into two broad categories: crystalloids and colloids. The fundamental physiologic difference between these two is that colloid solutions generate protein or colloid osmotic pressure (COP).

How safe is gelatin? A systematic review and meta-analysis of gelatin-contain…

Gelatin is a widely used synthetic colloid resuscitation fluid. We undertook a systematic review and meta-analysis of adverse effects in randomized and nonrandomized studies comparing gelatin with crystalloid or albumin for treatment of hypovolemia. Multiple databases were searched systematically without language restrictions until August 2015. We assessed risk of bias of individual studies and…