Eff ect of roflumilast on exacerbations in patients with severe chronic obstr…

Roflumilast reduces exacerbations in patients with severe chronic obstructive pulmonary disease. Its eff ect in patients using fi xed combinations of inhaled corticosteroids and longacting β2 agonists is unknown. We postulated that rofl umilast would reduce exacerbations in patients with severe chronic obstructive pulmonary disease at risk for exacerbations, even in combination with inhaled co…

Roflumilast with long-acting b2-agonists for COPD: influence of exacerbation …

The oral, selective phosphodiesterase type-4 inhibitor roflumilast reduces exacerbations and improves lung function in patients with severe-to-very severe chronic obstructive pulmonary disease (COPD). We investigated the efficacy and safety of roflumilast used concomitantly with long-acting b2- agonists (LABAs) to reduce exacerbations, and the influence of exacerbation history. Pooled data wer…

The Oxford-Durham Study: A Randomized, Controlled Trial of Dietary Supplement…

Developmental coordination disorder (DCD) affects
5% of school-aged children. In addition to the core deficits in motor function, this condition is associated commonly with difficulties in learning, behavior, and psychosocial adjustment that persist into adulthood. Mounting evidence suggests that a relative lack of certain polyunsaturated fatty acids may contribute to related neurodevelopm…

Docosahexaenoic Acid for Reading, Cognition and Behavior in Children Aged 7�…

Omega-3 fatty acids are dietary essentials, and the current low intakes in most modern developed countries are believed to contribute to a wide variety of physical and mental health problems. Evidence from clinical trials indicates that dietary supplementation with long-chain omega-3 may improve child behavior and learning, although most previous trials have involved children with neurodevel…

Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attenti…

Several studies have demonstrated differences in omega-3 fatty acid composition in plasma and in erythrocyte membranes in patients with attention-deficit/hyperactivity disorder (ADHD) compared with unaffected controls. Omega-3 fatty acids have anti-inflammatory properties and can alter central nervous system cell membrane fluidity and phospholipid composition. Cell membrane fluidity can alter s…

Cognitive enhancement by omega-3 fatty acids from child-hood to old age: Find…

Omega-(n)-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are major components of neuronal membranes and have a wide range of functions, from modulating synaptic plasticity and neurochemistry, to neuroimmune-modulation and neuroprotection. Thus, it is not surprising that n-3 PUFA are widely acknowledged to have cognitive-enhancing effe…

Low Blood Long Chain Omega-3 Fatty Acids in UK Children Are Associated with P…

Omega-3 long-chain polyunsaturated fatty acids (LC-PUFA), especially DHA (docosahexaenonic acid) are essential for brain development and physical health. Low blood Omega-3 LC-PUFA have been reported in children with ADHD and related behavior/learning difficulties, as have benefits from dietary supplementation. Little is known, however, about blood fatty acid status in the general child popul…

Glucosamine and Chondroitin Sulfate Are Effective in the Management of Osteoa…

The use of glucosamine and chondroitin sulfate for the symptomatic treatment of osteoarthritis has been a subject of controversy for several reasons. First, the medical community in general took offense at the title of Theodosakis’ book, The Arthritis Cure. Second, the medical community is becoming divided into “traditional” and “alternative” camps with deep skepticism between them. …

Glucosamine and chondroitin sulfate: biological response modifiers of chondro…

To test the hypothesis that chondrocytes are more responsive to the chondroprotective agents, glucosamine (glcN) and chondroitin sulfate (CS), under in vitro conditions simulating in vivo joint stress.

Glucosamine and Chondroitin for Treating Symptoms of osteoarthritis: Evidence…

Edition

-

ISBN/ISSN

-

Collation

-

Series Title

-

Call Number

-