Alleviating Effect of Phyllanthus niruri on Sensorimotor and Cognitive Change…

Studies in animal models and humans have shown that chlorpyrifos (CPF) causes sensorimotor and cognitive changes. Apart from inhibiting acetylcholinesterase (AChE), the induction of oxidative stress is one of the other molecular mechanisms implicated in OP-evoked toxicity. The present study evaluated the alleviating effect of Phyllanthus niruri, a flavonoid rich plant, on subacute CPF-evoked se…

Safety of Favipiravir for Treatment of COVID-19: Latest Systematic Review

Adverse event studies of favipiravir used to treat COVID-19 have been ongoing since it was established as a treatment option. A better understanding of the side effects of favipiravir from recent studies is important for developing and assessing the introduction of effective treatments for COVID-19

A comparison of efficacy and safety of 2-year telbivudine and entecavir treat…

There are limited data comparing the clinical outcomes between telbivudine and entecavir. We consecutively enrolled 115 telbivudine-naive and 115 entecavir-naive chronic hepatitis B patients, who were matched for age, sex, hepatitis B e antigen (HBeAg) status and cirrhosis, and treated for at least 2 years or less than 2 years but had developed resistance. Except for the rate of HBeAg seroconve…

Effect of partial fatty acid oxidation inhibition with trimetazidine on morta…

The aim of this cohort study was to retrospectively evaluate, in patients with chronic heart failure (CHF), the long term effect of trimetazidine (TMZ) on morbidity and mortality

Bactericidal Activity of Low-Dose Clindamycin Administered at 8- and 12-Hour …

Twelve volunteers received 300 mg of clindamycin intravenously (i.v.) or orally (p.o.) administered every 8 h (q8h) or q12h by random assignment over four study periods. Serum bactericidal titers were determined for each regimen against two isolates each of Staphylococcus aureus, Streptococcus pneumoniae (one penicillinsensitive isolate and one penicillin-resistant isolate), and Bacteroides fra…

The Culture and Sensitivity Pattern of Urinary Tract Infections in Females of…

Most common urinary tract pathogen in females (reproductive age group) is E. coli and amikacin is the most effective drug. It is suggested that females should be regularly checked and examined by visiting the clinicians. They should be promptly treated after the proper investigations

A Comparison of efficacy between two natural exogenous surfactant preparation…

The Mortality and various morbidity rates have been substantially reduced by means of exofenous replacement, the cornerstoe in the treatment of respiratory distress syndrome (RDS) in premature infants

The Antihyperglycemic Drug a-Lipoic Acid Stimulates Glucose Uptake via Both G…

The cofactor of mitochondrial dehydrogenase complexes and potent antioxidant a-lipoic acid has been shown to lower blood glucose in diabetic animals. a-Lipoic acid enhances glucose uptake and GLUT1 and GLUT4 translocation in 3T3-L1 adipocytes and L6 myotubes, mimicking insulin action.

Pemirolast potassium 0.1% ophthalmic solution is an effective treatment for a…

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A Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive C…

It remains uncertain whether the choice of resuscitation fluid for patients in intensive care units (ICUs) affects survival. We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a heterogeneous population of patients in the ICU.