An Open Pilot Study of The Efficacy and Safety of Polygeline in Adult Subject…

There were 43 subjects who completely participated in this study and included in analysis. From baseline levels, haematocrite decreased in first 6 hours during fluid treatment. This decrement persisted in 48 hours of observation. Statistical analysis with ANOVA test showed the significant differences of haematocrite level during observation (Sum of square between groups 495 and within group 484…

Evidence-based Colloid Use in the Critically Ill: American Thoracic Society C…

Critical care clinicians have the opportunity to choose among several intravenous solutions for fluid replacement. These fall into two broad categories: crystalloids and colloids. The fundamental physiologic difference between these two is that colloid solutions generate protein or colloid osmotic pressure (COP).

How safe is gelatin? A systematic review and meta-analysis of gelatin-contain…

Gelatin is a widely used synthetic colloid resuscitation fluid. We undertook a systematic review and meta-analysis of adverse effects in randomized and nonrandomized studies comparing gelatin with crystalloid or albumin for treatment of hypovolemia. Multiple databases were searched systematically without language restrictions until August 2015. We assessed risk of bias of individual studies and…

EFFICACY OF POLYGELINE PRELOADING IN PREVENTION OF HYPOTENSION FOLLOWING CSEA

One hundred ASA grade I and II patients in the age group of 18 to 60 years of either sex undergoing lower abdominal or lower limb surgeries under combined spinal epidural anaesthesia (CSEA) using 0.5% bupivacaine were studied for efficacy of polygeline preloading as compared to equal volume of ringer's lactate for prevention of hypotension. They were randomly divided in two groups of 50 each. G…

National Consensus on Management of Dyspepsia and Helicobacter pylori Infection

Dyspepsia is one of numerous general complaints, which is commonly encountered by doctors of various disciplines. In daily practice, the complaint is not only limited for gastroenterologists. Knowledge on pathophysiology of dyspepsia have been developing continuously since a scientific investigation has been started in 1980’s, which considers Helicobacter pylori as one of key factor in managi…

Management of Functional Dyspepsia

The Rome III consensus committee defined dyspepsia as the presence of any of the following symptoms: postprandial fullness, early satiation, epigastric pain, and epigastric burning. Episodes of dyspepsia (Greek dys: bad, peptein: digestion) occur occasionally in every individual, but the entity of functional (“non-ulcer”) dyspepsia is a more chronic condition, present for at least 3 months…

Effects of Proton-Pump Inhibitors on Functional Dyspepsia: A Meta-analysis of…

The aim of this study was to assess systematically the efficacy of proton pump inhibitors (PPIs) in the treatment of functional dyspepsia compared with placebo and to determine if any difference in the response exists between symptom subgroups of functional dyspepsia.

A comparison of omeprazole, lansoprazole and pantoprazole in the maintenance …

Proton pump inhibitors are effective for the healing of oesophagitis. Standard doses of omeprazole, lansoprazole or pantoprazole are suf®cient for healing in mild to moderate cases of oesophagitis.

Omeprazole: Effective, Convenient Therapy for Zollinger-Ellison Syndrome

The acute and long-term effects of omeprazole on gastric acid secretion were examined in 11 patients with Zollinger-Ellison syndrome. Basal gastric acid secretion was inhibited by 50% 3 h after a single 60-mg dose of omeprazole and 78% 4 h after administration of omeprazole. Patients were treated with a single daily dose of omeprazole, and the dose requirement was defined as the lowest dose of…

Activities of B-lactams, fluoroquinolones, amikacin and fosfomycin alone and …

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