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Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Sk…
Astaxanthin (ASX), a xanthophyll carotenoid derived from microalgae Haematococcus pluvialis, mitigating skin photoaging and age-related skin diseases by its antioxidant and anti-inflammatory effects in animal studies. Objective: The aim was to systematically evaluate if ASX applications have anti-ageing effects in humans. Methods: A comprehensive search of PubMed, Scopus and Web of Science foun…
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Members of Antioxidant Machinery and Their Functions
overpopulation, scientific knowledge on antioxidants is important since most of the diseases are mediated through reactive oxygen species (ROS). An antioxidant is a molecule that inhibits the oxidation of another molecule. Antioxidants may work through single or combined mechanisms, and based on their activity, they have been categorized into primary, secondary, and tertiary antioxidants. Enzy…
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Antioxidant and anti-inflammatory properties of a Cucumis melo LC. extract ri…
The present studywas conducted to evaluate in vitro and in vivo the antioxidant and anti-inflammatory properties of a cantaloupe melon (Cucumis melo LC., Cucurbitaceae) extract (CME) selected for its high superoxide dismutase activity. Peritoneal macrophages were pre-activated in vitro with 300 IU of interferon- (IFN-) and were then challenged in culture with IgGl/anti-IgG1 immune complexes (…
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Ondansetron: recommended antiemetics for patients with acute pancreatitis? a …
Ondansetron administration is a common antemetic of acute pancreatitis therapy in the intensive care unit (ICU), but its actual association with patients’ outcomes has not been confirmed. The study is aimed to determine whether the multiple outcomes of ICU patients with acute pancreatitis could benefit from ondansetron.
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Effect of ondansetron on nausea and vomiting after middle ear surgery during …
The efficacy of ondansetron 4 mg and 8 mg was compared with placebo in the reduction of postoperative nausea, retching and vomiting (PONV) after middle ear surgery during general anaesthesia, in 75 patients, in a double-blind and randomized study. Both doses of ondansetron were predictors for a decrease in PONV and the number of doses of rescue antiemetic needed per patient (droperidol: from 0.…
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Ondansetron-induced QT prolongation among various age groups: a systematic re…
d Ondansetron is a selective 5-hydroxytryptamine type 3 serotonin-receptor antagonist with antiemetic properties used inadvertently in the emergency department for controlling nausea. However, ondansetron is linked with a number of adverse efects, including prolongation of the QT interval. Therefore, the purpose of this meta-analysis was to assess the occurrence of QT prolongation in pediatri…
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Ondansetron oral disintegrating tablets for the prevention of postoperative v…
Strabismus surgery in pediatric patients is associated with a high incidence of postoperative nausea and vomiting (PONV). Ondansetron disintegrating tablets (ODT), an oral freeze-dried formulation of the 5-HT3 antagonist, are well-tolerated and have been shown to reduce chemotherapy-induced vomiting. The purpose of this study was to assess the effi cacy of the ODT in preventing postoperative v…
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Treatment of hyperemesis gravidarum with the 5-HT3 antagonist ondansetron (Zo…
Ondansetron is a 5-hydroxytryptamine receptor antagonist which is known to be a highly effective anti-emetic drug for chemotherapy-associated nausea and vomiting and for postoperative nausea. We report here a case where ondansetron was used in severe hyperemesis gravidarum to avoid parenteral nutrition. The drug was used intermittently in every trimester with no apparent adverse effects on mo…
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EFFECT OF CENTELLA ASIATICA ON MILD COGNITIVE IMPAIRMENT (MCI) AND OTHER COMM…
Centella asiatica is an herb used since ancient time in Ayurveda to improve mild cognitive functioning. The current study aimed to managing the cognitive functioning in elderly with mild cognitive impairment (MCI) and other age related problems. MCI is a serious problem which may be converted into Alzheimer disease. Although the concept of MCI is based on the presence of specific cognitive def…
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EFFECT OF CENTELLA ASIATICA LEAVES EXTRACT ON HIPPOCAMPAL CA3 NEURONS: A MORP…
Centella asiatica is a perennial herbaceous creeper, growing in moist soil. It has anti-thrombotic, antibacterial and antiinflammatory properties. In Ayurvedic medicine, Centella asiatica is used extensively as brain tonic to enhance the neural function, learning and memory. In the present study, the neuroprotective role of Centella asiatica (CeA) leaves extract on hippocampal CA3 neurons again…
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