Comparison of Sevoflurane versus Propofol under Auditory Evoked Potential Mon…

General anesthesia is used for most major surgeries, and the most common side effects include headache, nausea, vomiting, and sore throat. Major breast surgery is associated with a high incidence of postoperative nausea and vomiting (PONV). We compared the postoperative nausea and vomiting of propofol-based total intravenous anesthesia (TIVA) and sevoflurane (SEVO) anesthesia under auditory evo…

Propofol and survival: an updated meta-analysis of randomized clinical trials

Propofol is one of the most widely used hypnotic agents in the world. Nonetheless, propofol might have detrimental effects on clinically relevant outcomes, possibly due to inhibition of other interventions’ organ protective properties. We performed a systematic review and meta-analysis of randomized controlled trials to evaluate if propofol reduced survival compared to any other hypnotic agen…

Effect of rebamipide on prostaglandin receptors-mediated increase of inflamma…

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Effect of Rebamipide, a Novel Antiulcer Agent, on Helicobacter pylori Adhesio…

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Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhi…

Endoscopic submucosal dissection (ESD) is useful for treating gastric tumors. Several trials have shown the efficacy of 4 or 8 weeks of proton pump inhibitor (PPI) administration for post-ESD ulcers. However, if the size of the post-ESD ulcer is larger than predicted, PPI administration alone might not be sufficient for the ulcer to heal within 4 weeks. We examined the efficacy of a combination…

Anti-inflammatory Effects of Rebamipide According to Helicobacter pylori Stat…

The aim of the study was to investigate the effects of rebamipide on symptom, histology, endogenous prostaglandin, and mucosal oxygen free radicals in chronic erosive gastritis (CEG) patients by using sucralfate as a control. The trial also examined whether Helicobacter pylori infection would affect rebamipide-induced protection. A total of 453 endoscopy-confirmed CEG patients from 11 hos…

Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness…

The purpose of this report was to update the 2006 International League Against Epilepsy (ILAE) report and identify the level of evidence for long-term efficacy or effectiveness for antiepileptic drugs (AEDs) as initial monotherapy for patients with newly diagnosed or untreated epilepsy. All applicable articles from July 2005 until March 2012 were identified, evaluated, and combined with th…

The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for…

Valproate is widely accepted as a drug of first choice for patients with generalised onset seizures, and its broad spectrum of efficacy means it is recommended for patients with seizures that are difficult to classify. Lamotrigine and topiramate are also thought to possess broad spectrum activity.

Seizures in Children

Seizures are the most common pediatric neurologic disorder, with 4% to 10% of children suffering at least one seizure in the first 16 years of life [1]. The incidence is highest in children younger than 3 years of age, with a decreasing frequency in older children

Safety and Efficacy of Privigen®, a Novel 10% Liquid Immunoglobulin Preparat…

The present study was designed to evaluate the efficacy and safety of a novel, 10% liquid formulation of intravenous immunoglobulin, stabilized with 250 mmol/L L-proline (Privigen®), in patients with primary immunodeficiency disease