COMPARATIVE EFFICACY OF LOW- AND HIGHMOLECULAR WEIGHT INTRA-ARTICULAR HYALURO…

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Viscosupplementation for the treatment of osteoarthritis of the knee

To assess the effects of viscosupplementation in the treatment of OA of the knee. The products were hyaluronan and hylan derivativesrn(Adant, Arthrum H, Artz (Artzal, Supartz), BioHy (Arthrease, Euflexxa, Nuflexxa), Durolane, Fermathron, Go-On, Hyalgan, HylanrnG-F 20 (Synvisc Hylan G-F 20), Hyruan, NRD-101 (Suvenyl), Orthovisc, Ostenil, Replasyn, SLM-10, Suplasyn, Synject and Zeelrncompositum).

The role of intra-articular hyaluronan (Sinovial) in the treatment of osteoar…

Osteoarthritis (OA) leads to significant pain and disability. For pain relief, a tailored approach using non-pharmacological and pharmacological therapies is recommended. If adequate symptom relief is not achieved with acetaminophen, other pharmacological options include non-steroidal anti-inflammatory drugs (NSAIDs), topical analgesics, intra-articular corticosteroids and intraarticular hyalur…

Which is most pungent: isoflurane, sevoflurane or desflurane?

We compared the pungency and tolerability of three inhaled anaesthetics in a randomized, double-blind study. Eighty-one unpremedicated patients (n=27, each group) inhaled 2 MAC of isoflurane (2.3%), desflurane (12%) or sevoflurane (4%) for 60 s from an anaesthetic breathing circuit via a mask. Two blinded observers recorded coughing, complaints of burning and irritation, and how long the in…

Comparative Study of Sevoflurane with Other Inhalation Agents

Until 1950, there were few volatile anesthetic agents, such as diethyl ether and chloroform. It was dangerous or harmful to use them because they were explosive or caused cellular toxicity. In 1956, halothane was synthesized. Halothane is a powerful nonflammable anesthetic agent, and it quickly became widely used.

Sevoflurane: Are There Differences in Products?

Sevoflurane is currently available in the United States from two manufacturers: Ultane
(Abbott Laboratories, Inc.) and a generic product, Sevoflurane Inhalation Anesthetic (Baxter Healthcare Corp.). These products are rated therapeutically equivalent by the Food and Drug Administration, but there are some differences. Ultane is made in a single-step synthetic process and generic sevoflurane i…

Sevoflurane Formulation Water Content Influences Degradation by Lewis Acids i…

Sevoflurane is produced by several manufacturers. Currently marketed sevoflurane formulations differ in their method of synthesis, impurities, containers in which they are sold, and water content. Of the various types of chemical degradation to which sevoflurane is susceptible, the most pertinent is degradation by Lewis acids (such as metal oxides and metal halides) to hydrofluoric acid and ot…

Sevoflurane causes less arrhythmias than desflurane after off-pump coronary a…

Volatile anesthetics provide myocardial protection during cardiac surgery. Sevoflurane and desflurane are both efficient agents that allow immediate extubation after off-pump coronary artery bypass grafting (OPCABG). This study compared the incidence of arrhythmias after OPCABG with the two agents.

Sevoflurane Formulation Water Content Influences Degradation by Lewis Acids i…

Sevoflurane is produced by several manufacturers. Currently marketed sevoflurane formulations differ in their method of synthesis, impurities, containers in which they are sold, and water content. Of the various types of chemical degradation to which sevoflurane is susceptible, the most pertinent is degradation by Lewis acids (such as metal oxides and metal halides) to hydrofluoric acid and o…

Protective effect of sevoflurane on myocardial ischemia-reperfusion injury: a…

Myocardial ischemia-reperfusion (I/R) injury significantly impacts recovery in both cardiac and noncardiac surgeries, potentially leading to severe cardiac dysfunction. Sevoflurane, a volatile anesthetic, is reputed for its protective effects against myocardial I/R injury, although evidence remains inconclusive. This systematic review and meta-analysis aim to clarify the cardioprotective eff…