Global Initiative for Chronic Obstructive Lung Disease Global Initiative for …

Attention health care professionals: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) group has released their Pocket Guide to COPD Diagnosis, Management and Prevention – A Guide for Health Care Professionals, updated for 2016.

Global Strategy for Asthma Management and Prevention. (2017 update)

Asthma is a serious health problem throughout the world. During the past two decades, many scientific advances have improved our understanding of asthma and ability to manage and control it effectively. However, recommendations for asthma care need to be adapted to local conditions, resources and services

More Epidural than Intravenous Sufentanil is Required to Provide Comparable P…

The extent to which epidurally administered sufentanil acts directly on spinal opioid receptors remains controversial. We tested the hypothesis that smalldose boluses of sufentanil, given epidurally or IV, provide comparable analgesia at similar plasma sufentanil concentrations. The lipophilicity of sufentanil makes it likely to be absorbed into fat surrounding the epidural space

Early postoperative cognitive recovery after remifentanil– propofol or sufe…

This study was designed to evaluate early postoperative cognitive recovery after total intravenous anaesthesia with remifentanil–propofol or sufentanil–propofol in patients undergoing craniotomy for supratentorial expanding lesions

Atorvastatin: A Review of its Use in the Primary Prevention of Cardiovascula…

Atorvastatin (Lipitor®) is an HMG-CoA reductase inhibitor with well documented lipid-lowering effects. It has recently been evaluated for the primary prevention of major cardiovascular events in patients with type 2 diabetes mellitus without elevated serum low-density lipoprotein (LDL)-cholesterol levels.

Effect of Very High-Intensity Statin Therapy on Regression of Coronary Athero…

Prospective, open-label blinded end-points trial (A Study to Evaluate the Effect of Rosuvastatin on Intravascular Ultrasound-Derived Coronary Atheroma Burden [ASTEROID]) was performed at 53 community and tertiary care centers in the United States, Canada, Europe, and Australia. A motorized IVUS pullback was used to assess coronary atheroma burden at baseline and after 24 months of treatment. Ea…

Atorvastatin (Calcium)

Atorvastatin is a synthetic competitive inhibitor of 3-hydroxy-3-methlyglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step incholesterol biosynthesis

Effects of Atorvastatin on Early Recurrent Ischemic Events in Acute Coronary …

BLOOD CHOLESTEROL LOWERing with statins has been regarded as a long-term strategy to reduce death and ischemic cardiovascular events in patients with stable coronary heart disease, with significant effects evident after approximately 2 years of treatment

The polymorphism of statins and its effect on their physicochemical properties

Polymorphism of pharmaceutical substances has a significant impact on their physicochemical properties, durability, bioavailability and consequently on their pharmacological activity. Solid dosage forms may exist in both crystalline and amorphous forms. Amorphous varieties are characterized by higher solubility and dissolution rates, while crystalline forms show greater purity and storage stab…

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the…

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