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Water-soluble vitamins: research update
For more than 50 years, the Food and Nutrition Board of the National Academy of Sciences has been reviewing nutrition research and defining nutrient requirements for healthy people, referred to as the recommended dietary allowances (RDA). As new nutrition research is published, the importance of vitamins as vital nutrients is underscored, and new physiologic roles and applications to human heal…
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Update on Safety Profiles of Vitamins B1, B6, and B12: A Narrative Review
The neurotropic B vitamins B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) are essential for proper functioning of the nervous system. Deficiencies may induce neurological disorders like peripheral neuropathy (PN) and mainly occur in vulnerable populations (eg, elderly, diabetics, alcoholics). As epidemiologic cohort studies raised safety concerns about vitamin B6/B12 intake being potentia…
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ESPEN Guidelines on Parenteral Nutrition: Adult Renal Failure
Among patients with renal failure, those with ARF and critical illness represent by far the largest group unergoing artificial nutrition. ARF, especially in the ICU, seldom occurs as isolated organ failure but rather is a component of a much more complex metabolic environment, in the setting of the multiple organ failure. Nutritional programs for ARF patients must consider not only the metaboli…
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Guidelines for parenteral and enteral nutrition in geriatric patients in China
Based on the expert consensus on parenteral and enteral nutrition support for geriatric patients in China in 2013, domestic multidisciplinary experts were gathered to summarize the new evidence in the field of elderly nutritional support at home and abroad. The 2013 consensus was comprehensively updated and upgraded to a guideline by referring to the World Health Organization (WHO) guidelines …
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Current clinical aspects of parenteral nutrition in geriatric patients
Advancements in medicine, better diagnostics and zeal for a high quality of life have enabled many geriatric patients seeking medical attention for any type of illness. The elderly population is increasing globally and so does the number of such patients in hospital and critical care units. However, increased incidence of debilitating diseases in elderly makes them more prone to develop malnu…
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Vitamin C and Immune Function
Vitamin C is an essential micronutrient for humans, with pleiotropic functions related to its ability to donate electrons. It is a potent antioxidant and a cofactor for a family of biosynthetic and gene regulatory enzymes. Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C supports epithelial barrier function…
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Lyophilization/Freeze Drying - A Review
Freeze-drying is a method of removing water by sublimation of ice crystals from frozen material. Suitable parameters of process application allow us to obtain best quality products compared to products dried with traditional methods. In pharmaceutical field lyophilization has become important subject to ongoing development and its expansion. Lyophilization is common, but cost intensive and henc…
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Vitamin
Vitamin, any of several organic substances that are necessary in small quantities for normal health and growth in higher forms of animal life. Vitamins are distinct in several ways from other biologically important compounds such as proteins, carbohydrates, and lipids. Although these latter substances also are indispensable for proper bodily functions, almost all of them can be synthesized by a…
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Nutritional Support for Wound Healing
Healing of wounds, whether from accidental injury or surgical intervention, involves the activity of an intricate network of blood cells, tissue types, cytokines, and growth factors. This results in increased cellular activity, which causes an intensified metabolic demand for nutrients. Nutritional deficiencies can impede wound healing, and several nutritional factors required for wound repair…
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The Nutritional Management of Hepatic Encephalopathy in Patients with Cirrhos…
The assessment of nutritional status in patients with cirrhosis is problematic. In addition there are significant sex-related differences in body composition and in the characteristics of tissue loss which limit the usefulness of techniques based on measures of muscle mass and function in women. Techniques which combine subjective and objective variables provide reasonably accurate information…
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