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Evaluasi Penggunaan Antibiotik dan Profil Kuman pada Seksio Sesarea di Rumah …
Infeksi Luka Operasi (ILO) adalah salah satu komplikasi pembedahan yang paling umum terjadi di dunia, terutama di negara berkembang. Penggunaan antibiotik profilaksis sebelum operasi yang tepat dapat mengurangi ILO. Penelitian ini bertujuan untuk mengetahui profil penggunaan antibiotik dan kesesuaian penggunaan antibiotik pada seksio sesarea dengan peta kuman rumah sakit, Pedoman Penggunaan Ant…
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Typhoid fever: issues in laboratory detection, treatment options & concerns i…
Multidrug-resistant Salmonella enterica subsp. enterica serovar Typhi (resistant to ampicillin, chloramphenicol and cotrimoxazole), was significantly reduced with the increased usage of fluoroquinolones and azithromycin. This has led to declining multidrug resistance rates in Indiawith increasing ciprofloxacin nonsusceptibility rates and clinical failures due to azithromycin. However, for the …
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Pharmacokinetic Profile of Levofloxacin following Once-Daily 500-Milligram Or…
The pharmacokinetics of once-daily oral levofloxacin (study A) or intravenous levofloxacin (study B) in 40 healthy male volunteers were investigated in two separate randomized, double-blind, parallel-design, placebocontrolled studies. Levofloxacin at 500 mg or placebo was administered orally or intravenously as a single dose on day 1; daily oral or intravenous dosing resumed on days 4 to 10. I…
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A Multicenter, Randomized Study Comparing the Efficacy and Safety of Intraven…
Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of community-acquired pneumonia in adults. Patients received either intravenous and/or oral levofloxacin (500 mg once daily) or the comparative agents, parentera…
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Comparative Pharmacokinetics of Ciprofloxacin, Gatifloxacin, Grepafloxacin, L…
In an open, randomized, six-period crossover study, the pharmacokinetics of ciprofloxacin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin were compared after a single oral dose in 12 healthy volunteers (6 men and 6 women). The volunteers received 250 mg of ciprofloxacin, 400 mg of gatifloxacin, 600 mg of grepafloxacin, 500 mg of levofloxacin, 400 mg of moxifloxacin,…
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Oral bioavailability study of 500mg Levofloxacin in healthy volunteers: a pha…
Penelitian ini dilakukan untuk mengetahui apakah bioavailabilitas tablet levofloksasin 500 mg yang diproduksi oleh PT. Dexa Medica (Volequin) sebanding dengan bioavailabilitas produk pembanding. Parameter farmakokinetik yang dinilai dalam studi ini ialah kadar puncak (Cmax), waktu untuk mencapai kadar puncak (tmax), waktu paruh eliminasi (t1/2), luas daerah di bawah kur…
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Clinical Nutrition Guidelines and Summaries for Patients
This document is about the development of clinical nutrition guidelines and the importance of summaries of these for patients as well as the need for patient involvement in the development processes, the importance of health literacy and informed decision-making concerning food and nutrition
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ESPGHAN/ESPEN/ESPR guidelines on pediatric parenteral nutrition: Q7 Vitamins
A systematic literature search was conducted on 27/Dec/2014 including papers published between 2004 and 2014. In total, 150 abstracts were reviewed and an additional individual search was performed by the authors for each vitamin chapter, including searching the reference lists of selected papers. Some references from the previously published guidelines were preserved, where appropriate.
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The Role of Vitamin E in Immunity
Vitamin E is a fat-soluble antioxidant that can protect the polyunsaturated fatty acids (PUFAs) in the membrane from oxidation, regulate the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), and modulate signal transduction. Immunomodulatory effects of vitamin E have been observed in animal and human models under normal and disease conditions. With advances in und…
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B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review
The B-vitamins comprise a group of eight water soluble vitamins that perform essential, closely inter-related roles in cellular functioning, acting as co-enzymes in a vast array of catabolic and anabolic enzymatic reactions. Their collective effects are particularly prevalent to numerous aspects of brain function, including energy production, DNA/RNA synthesis/repair, genomic and non-genomic me…
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