Dietary Carotenoids, Vitamins A, C,rnand E, and Advanced Age-RelatedrnMacular…

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Meta-analysis of clinical studies with betahistine in Meniere’s disease and…

We present a meta-analysis of 12 double-blind, randomized, placebo-controlled clinical studies with betahistine in patients suffering from vestibular vertigo or Meniere’s disease, based on both published and unpublished data.

Betahistine in the treatment of Ménière’s disease

Ménière’s disease and related disease of the vestibular system are common and debilitating. Current therapy is multi-modal and includes drug therapy and lifestyle adaptations. Unfortunately many of the drugs used in treatment (particularly those used to control nausea) are sedative and hamper the process of vestibular compensation. Although betahistine (Serc®, BetaSerc®; Solvay Pharmaceut…

Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for control…

Intravenous (IV) formulations of proton pump inhibitors are effective for patients in whom oral therapy is not appropriate

A Review on Freeze Drying Process of Pharmaceuticals

Freeze-drying is a method of removing water by sublimation of ice crystals from frozen material. Suitable parameters of process application allow us to obtain best quality products compared to products dried with traditional methods. In pharmaceutical field lyophilization has become important subject to ongoing development and its expansion

Effect of intravenous application of esomeprazole 40 mg versus pantoprazole 4…

It has been demonstrated that therapy with proton pump inhibitors reduces recurrence of bleeding following initial endoscopic treatment of bleeding peptic ulcers

Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for control…

On days 1 and 5, intragastric pH was >4.0 significantly longer with esomeprazole than lansoprazole (least-squares means: day 1, 40.0% vs. 33.6%; day 5, 61.9% vs. 45.4%; both P < 0.0001). During the first 4 h of pH monitoring, intragastric pH was >4.0 significantly longer on days 1 and 5 with esomeprazole than lansoprazole (P < 0.0001). Kaplan–Meier estimates of median hours to stable pH >4.…

Esomeprazole 40 mg i.v. provides faster and more effective intragastric acid …

Once-daily dosing with esomeprazole 40 mg intravenously provides faster and more pronounced intragastric acid control than pantoprazole 40 mg intravenously

An extended 36-week oral esomeprazole improved long-term recurrent peptic ulc…

Patients with Rockall scores ≥6 have an increased risk of long-term peptic ulcer rebleeding. This study was aimed toward investigating whether an extended course of oral esomeprazole up to 1 year decreased ulcer rebleeding in such patients.

Pharmacokinetics of Esomeprazole in Critically Ill Patients

Esomeprazole, a potent proton pump inhibitor (PPI), is widely used for the prevention of stress ulcers in intensive care unit (ICU) patients.