Evaluation of vehicle substances on vitamin D bioavailability: A systematic r…

Vitamin D insufficiency is a common medical condition. Vitamin supplements can be ingested to improve vitamin D status. It is not known if the vehicle substance that is combined with the vitamin D tablet influences the bioavailability of vitamin D. The purpose of this review is to examine the impact of different vehicles on vitamin D bioavailability. A comprehensive literature search identified…

Assessing the severity of acute pulmonaryrnembolism: back to the future?

This editorial refers to ?Prognostic value of right ventricularrndysfunction or elevated cardiac biomarkers in patients withrnlow-risk pulmonary embolism: a systematic review andrnmeta-analysis?? by S. Barco et al.,

Prediction of stroke after cardiac catherization: no reason, no stroke

In this issue, Tokushige and colleagues incestigated the incidence of cerebrovascular compliactions detected by difussion-weighted, head-focused magnetic resonance imaging (MRI) within 48 hours after CAG and determined its clinical risk factor

The chemistry and biological activities of N-acetylcysteine

The outlined reactions only partially explain the diverse biological effects of NAC, and further studies are required for determining its ability to cross the cellmembrane and the blood–brain barrier as well as elucidating its reactions with components of cell signaling pathways

N-Acetylcysteine mucolysis in the management of chronic obstructive pulmonary…

To develop an efficient therapy for chronic obstructive pulmonary disease (COPD), N-acetylcysteine (NAC) has been tested as a medication that can suppress various pathogenic processes in this disease. NAC is a thiol compound, which provides sulfhydryl groups. NAC can act as a precursor of reduced glutathione and as a direct reactive oxygen species scavenger, hence regulating the redox status i…

Thyrotoxicosis: Diagnosis and Management

Thyrotoxicosis is the clinical manifestation of excess thyroid hormone action at the tissue level due to inappropriately high circulating thyroid hormone concentrations. Hyperthyroidism, a subset of thyrotoxicosis, refers specifically to excess thyroid hormone synthesis and secretion by the thyroid gland. We performed a review of the literature on these topics utilizing published data in PubMed…

Antioxidant activities of carotenes and xanthophylls

The purpose of this study was to assess the relative antioxidant activities of a range of carotenes and xanthophylls through the extent of their abilities to scavenge the ABTS "+ radical cation. The results show that the relative abilities of the carotenoids to scavenge the ABTS "÷ radical cation are influenced by the presence of functional groups with increasing polarities, such as carbonyl a…

Lutein, but Not Alpha-Tocopherol, Supplementation Improves Visual Function in…

Visual function in patients with age-related cataracts who received the lutein supplementsrnimproved, suggesting that a higher intake of lutein, through lutein-rich fruit and vegetables or supplements,rnmay have beneficial effects on the visual performance of people with age-related cataracts

A Study to evaluate the antimicrobial activity of feracrylum and its comparis…

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Citicoline Oral Solution in Glaucoma: Is There a Role in Slowing Disease Prog…

To assess the effect of citicoline on visual field rates of progression in patients with progressing glaucoma