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THE CONCEPTUAL AND CLINICAL PROBLEMS OF PARANEOPLASTIC SYNDROME IN ONCOLOGY A…
Symptomatology of oncological diseases consists not only of local symptoms caused by the primary malignancy or its metastases, but also by general systemic signs that are not directly connected with the tumor. These symptoms are mostly associated with auto-immunity or endocrine influences. In many cases, the source of paraneoplastic syndromes (PNS) is unknown. Nearly 15% of on-cological patient…
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Cancer Drug Toxicities and Anaesthesia
Cancer is now overtaking cardiac disease as the most common cause of death in Western societies. Perhaps the main reason for this is increased life expectancy at birth. However, elsewhere, cancer is also rising in incidence, due in no small part to chronic infections such as viral hepatitis. Given improved survival with aggressive and modern treatments, surgery is becoming more important in the…
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Anesthetics impact on cancer recurrence: What do we know?
Surgery is an important component of treatment in cancer patients. However, surgical stress, anesthesia, and perioperative analgesia interfere with the host immune defense mechanisms and may contribute to metastatic dissemination of malignant tumors and cancer progression. Little is known about the effects of anesthesia on tumor recurrence. In vivo studies and clinical data show some evidence t…
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Pharmacokinetics of levobupivacaine with epinephrine in transversus abdominis…
Transversus abdominis plane block is increasingly used for post-Caesarean section analgesia. Cases of toxicity and the limited pharmacokinetic information during pregnancy motivated this study. The objective of the study was to characterise and compare the pharmacokinetics of levobupivacaine with epinephrine in tranversus abdominis plane block, in post-Caesarean section patients and healthy vol…
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Wound Management
Clinicians should be familiar with the principles of wound management, including repair methods, risks for infection, tetanus prophylaxis, and appropriate use of antibiotics and diagnostic studies.
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Multifactorial Approaches for Correction of the Drooping Tip of a Long Nose i…
A long nose with a drooping tip is a major aesthetic problem. It creates a negative and aged appearance and looks worse when smiling. In order to rectify this problem, the underlying anatomical causes should be understood and corrected simultaneously to optimize surgical outcomes. The causes of a drooping tip of a long nose are generally classified into two mechanisms.
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The Crooked Nose: Principles of Treatment
Correction of the crooked nose is one of the most challenging procedures in rhinoplasty. The goals of the surgery are creation of a rigid and straight cartilaginous L-strut, correction of the deviated bony structures, and improvement of the nasal airway. Curvatures of the dorsal septum can be corrected with several techniques. Spreader grafts, cartilage batten grafts, or ethmoid bone grafts can…
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Neurological presentations of systemic disorders - Level 1 Encephalopathies i…
Metabolic encephalopathies frequently cause the consultation of a neurologist, both in the emergency room as well as for in-patients of the departments of internal medicine or surgery. More than 2/3 of the patients who are referred to an emergency unit with altered consciousness show electrolyte disturbances, endocrinologic disorders, metabolic encephalopathies or intoxications (Plum & Posner …
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The Classic: The Cervical Syndrome
The term Cervical Syndrome is used to classify a group of cases which presents definitely similar symptoms and clinical findings, the causative factor of which is irritation of the cervical nerve roots. To interpret adequately this syndrome one must have a knowledge of the anatomy and mechanics of the cervical spine, the segmental character of the cervical nerves, and the relationship between…
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Ultrasonography in the emergency department
Point-of-care ultrasonography (POCUS) is a useful imaging technique for the emergency medicine (EM) physician. Because of its growing use in EM, this article will summarize the historical development, the scope of practice, and some evidence supporting the current applications of POCUS in the adult emergency department. Bedside ultrasonography in the emergency department shares clinical applica…
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