The Crooked Nose: Principles of Treatment

Correction of the crooked nose is one of the most challenging procedures in rhinoplasty. The goals of the surgery are creation of a rigid and straight cartilaginous L-strut, correction of the deviated bony structures, and improvement of the nasal airway. Curvatures of the dorsal septum can be corrected with several techniques. Spreader grafts, cartilage batten grafts, or ethmoid bone grafts can…

Neurological presentations of systemic disorders - Level 1 Encephalopathies i…

Metabolic encephalopathies frequently cause the consultation of a neurologist, both in the emergency room as well as for in-patients of the departments of internal medicine or surgery. More than 2/3 of the patients who are referred to an emergency unit with altered consciousness show electrolyte disturbances, endocrinologic disorders, metabolic encephalopathies or intoxications (Plum & Posner …

The Classic: The Cervical Syndrome

The term Cervical Syndrome is used to classify a group of cases which presents definitely similar symptoms and clinical findings, the causative factor of which is irritation of the cervical nerve roots. To interpret adequately this syndrome one must have a knowledge of the anatomy and mechanics of the cervical spine, the segmental character of the cervical nerves, and the relationship between…

Ultrasonography in the emergency department

Point-of-care ultrasonography (POCUS) is a useful imaging technique for the emergency medicine (EM) physician. Because of its growing use in EM, this article will summarize the historical development, the scope of practice, and some evidence supporting the current applications of POCUS in the adult emergency department. Bedside ultrasonography in the emergency department shares clinical applica…

Occult Traumatic Pneumothorax: Diagnostic Accuracy of Lung Ultrasonography in…

Twenty-five traumatic PTXs were detected in the 218 hemithoraxes (109 patients; 2 patients had a bilateral PTX) evaluated by spiral CT scan; of these, only 13 of 25 PTXs (52%) were revealed by chest Rx (sensitivity, 52%; specificity, 100%), while 23 of 25 PTXs (92%) were identified by lung US with one false-positive result (sensitivity, 92%; specificity, 99.4%). In 20 of 25 cases, there was agr…

Objective and Structured Assessment of Lung Ultrasound Competence : A Multisp…

This assessment tool provides a relevant, valid, and feasible method for evaluation of operator competence in point-of-care lung ultrasound across multiple specialties. This allows for a more individualized assessment of competence than current recommendations.

Update on the Management of Antibiotic Allergy

Drug allergy to antibiotics may occur in the form of immediate or non-immediate (delayed) hypersensitivity reactions. Immediate reactions are usual-ly IgE-mediated whereas non-immediate hypersensitivity reactions are usually non-IgE or T-cell mediated. The clinical manifestations of antibiotic allergy may be cutaneous, organ-specific (e.g., blood dyscracias, hepatitis, interstitial nephritis), …

Diagnosis and management of drug hypersensitivity reactions

The present article addresses the advances in the diagnosis and management of drug hypersensitivity reactions that were discussed in the 4th Drug Hypersensitivity Meeting held in Rome in April 2010. Such reactions can be classified as immediate or nonimmediate according to the time interval between the last drug administration and onset.

Macroalgal Fucoidan extracts: a new opportunity for marine cosmetics

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Effect of Fucoidan on the Biotinidase Kinetics in Human Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is difficult to treat with anticancer drugs. Therefore, development of new drugs for HCC is required.