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Hump Nose Correction in Asians
Nasal hump surgery is frequently regarded as a reduction surgery in most Western rhinoplasty textbooks and referred to as reduction rhinoplasty. Although there are exceptions, most Asian hump noses have a small hump, and is frequently associated with a low nasal dorsum and underprojection of the nasal tip. Therefore, correcting a hump nose in Asians has distinct differences in concept and tech…
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The History of ultrasound
Over the past 40 years, ultrasound has become an important diagnostic modality. Its potential as a leader in medical diagnostic imaging was recognized in the 1930s and 1940s, when Theodore Dussik and his brother Friederich attempted to use ultrasound to diagnose brain tumors. It was not until the 1970s, however, that the work of these and other pioneers of ultrasound research truly came to frui…
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Cardiac Shock Care Centers
Despite advances over the past decade, the incidence of cardiogenic shock secondary to acute myocardial infarction has increased, with an unchanged mortality near 50%. Recent trials have not clarified the best strategies in treatment. While dedicated cardiac shock centers are being established, there are no standardized agreements on the utilization of mechanical circulatory support and the tim…
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Aspiration pneumonia and pneumonitis: a spectrum of infectious/noninfectious …
Aspiration pneumonia and pneumonitis are part of the pneumonia continuum and share similarities in pathophysiology, microbiology, and treatment. Modern microbiology demonstrates that the lung is not sterile, and isolates in aspiration pneumonia frequently include aerobes or mixed cultures. Treatment for aspiration pneumonia should include antibiotic coverage for oral anaerobes, aerobes associat…
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Progress in the monitoring of direct oral anticoagulant therapy
The availability of direct oral anticoagulants (DOACs) has led to a paradigm shift in the field of anticoagulation, with DOACs increasingly being prescribed for patients in preference to vitamin K antagonists and low molecular weight heparin. Despite good experience with the use of these agents at fixed doses, there are clinical scenarios where monitoring is recommended. Data from phase III st…
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Pola kepekaan antibiotika Escherichia coli yang diisolasi dari berbagai spesi…
Escherichia coli adalah bakteri fakultatif anaerob, berbentuk batang, bersifat gram negatif, dan merupakan flora normal intestinal. E. coli juga merupakan bakteri yang paling sering menyebabkan infeksi saluran kemih dan infeksi nosokomial. Resistensi E. coli terhadap berbagai antibiotika telah banyak dilaporkan, khususnya antibiotika golongan β-laktam. Tujuan penelitian ini adalah untuk mengis…
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Teamwork Assessment Tools in Obstetric Emergencies: A Systematic Review
Team-based training and simulation can improve patient safety, by improving communication, decision making, and performance of team members. Currently, there is no general consensus on whether or not a specific assessment tool is better adapted to evaluate teamwork in obstetric emergencies. The purpose of this qualitative systematic review was to find the tools available to assess team effectiv…
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Obstetrics and Gynecology Emergencies
This issue of Critical Care Clinics featuring Obstetrics and Gynecologic Emergencies began 20 years ago when a rather new obstetrician found herself knee deep in trouble with a patient experiencing an amniotic fluid embolism. Fortunately, the critical care team led by a very experienced intensivist arrived quickly, and because a multidisciplinary approach was taken, the patient experienced a ve…
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Photosensitive epilepsy : Robust clinical efficacy of a selective GABA potent…
The objective of this phase 2a study was to assess the activity of PF-06372865, a positive allosteric modulator (PAM) of α2/3/5 subunit-containing GABAA receptors with minimal activity at α1-containing receptors, which are believed to mediate many of the adverse events associated with benzodiazepines, in the epilepsy photosensitivity model as a proof-of-principle of efficacy
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Histopathology of diffusion imaging abnormalities in cerebral amyloid angiopathy
We sought to determine the underlying mechanism for altered white matter diffusion tensor imaging (DTI) measures at the histopathologic level in patients with cerebral amyloid angiopathy (CAA).
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