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Serum Uric Acid and the Renin Angiotensin System in Hypertension
To study whether the renin-angiotensin system is related to hyperuricemia in hypertension, the serum concentration of uric acid was determined in 96 patients with various types of hypertension and various degrees of plasma renin activity (PRA). In malignant hypertension, both PRA and the serum uric acid level were higher than in essential hypertension; but in primary aldosteronism or desoxycort…
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Relationships between serum uric acid and blood pressure, metabolic variables…
These data provide evidence that similarly to what described in western Europe, in central and eastern European countries SUA values are closely related to metabolic alterations, including diabetes mellitus, to renal insuffi ciency and CV risk profi le. At variance from other studies, however, no relationship was found with BP control.
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Sleep loss and circadian disruption in shift work: health burden and management
Nearly 1.5 million Australians are employed in shift work, representing 16% of the working population. Shift work is associated with adverse health, safety and performance outcomes. Circadian rhythm misalignment, inadequate and poor-quality sleep, and sleep disorders are thought to contribute to these associations.
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Circadian phase-shifting by light: Beyond photons
Circadian entrainment to the solar light:dark schedule is thought to be maintained by a simple photon counting method. According to this hypothesis, the pacemaker adjusts the phase of the body’s endogenous rhythms in accordance to the intensity and duration with which it encounters a perceived twilight signal. While previous data have generally supported the hypothesis, more recent analysis h…
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Lung Ultrasound: The Emerging Role of Respiratory Therapists
Lung ultrasound is a point-of-care imaging tool that is routinely used in acute care medicine. Traditionally, radiology physicians were the primary practitioners of diagnostic ultrasound, but with the recognition of its importance in intensive care medicine, critical care physicians have also adopted this practice. Within the intensive care unit inter-professional team is the respiratory th…
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Penggunaaan ultrasound di anestesi obstetri
Insidensi masalah medis kompleks diantara populasi obstetrik semakin meningkat, dan anestesia untuk pasien parturient rentan terhadap kompleksitas ini. USG memberikan visualisasi yang akurat terhadap struktur anatomis internal yang bisa membantu asesmen kondisi klinis dan meningkatkan keamanan intervensi terapeutik. Prosedur USG dalam anestesi obstetrik telah digunakan dalam memandu blokade neu…
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Novel therapies for diabetic kidney disease
Over the past 30 years there have been many complementary therapies developed to achieve glycemic control and have an impact on cardiovascular outcomes, as well as reduce the risk of microvascular disease. The 2 most notable new entries have been the sodium–glucose cotransporter 2 (SGLT2) inhibitors and the glucagon-like peptide-1 (GLP-1) agonists. Both these classes of agents have demonstra…
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Mineralocorticoid Antagonism and Diabetic Kidney Disease
Type 2 diabetes (T2D) is associated with an increased risk of diabetic kidney disease (DKD), cardiovascular disease, and heart failure, in part through activation of the renin-angiotensin-aldosterone system (RAAS). Although recent cardiovascular outcome trials have identified newer therapeutic agents such as sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1)-…
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Cardiovascular outcomes in diabetic kidney disease: insights from recent clin…
The prevalence of type 2 diabetes is catalyzing a pandemic in kidney disease, with ensuing cardiovascular complications. The effort to identify antidiabetic agents capable of promoting benefits that go beyond the bounds of glucose control has produced remarkable outcomes in recent cardiovascular outcomes trials in patients with type 2 diabetes mellitus, many of whom have diabetic kidney disease.
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Traumatic Abruptio Placenta Scale (TAPS): a proposed grading system of comput…
Placental abruption (PA) is one of the worst possible manifestations of injury in the pregnant trauma patient with ultrasound as the current initial imaging examination of choice, despite its known limitations in placental evaluation. Pregnant patients who undergo computed tomography (CT) for evaluation of potential maternal injuries provide an additional source of imaging for placental evalua…
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