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Metabolic Syndrome
Metabolic syndrome is a cluster of conditions — increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels — that occur together, increasing your risk of heart disease, stroke and diabetes
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Facts About Metabolic Diseases of Muscle
Metabolic diseases of muscle were first recognized in the second half of the 20th century. Each of these disorders is caused by a different genetic defect that impairs the body’s metabolism, the collection of chemical changes that occur within cells during normal functioning.
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Primary sarcoma of the lung: A very rare diagnosis and poor prognosis
Primary lung sarcoma is a very rare malignant tumor, accounting for less than 0.5% of all lung tumors. We describe the case of a 50-year-old man who presented with primary pulmonary sarcoma. X-ray chest and thoracic computed tomography (CT) revealed a 40 mm Χ 60 mm mass in the right upper lobe. Biopsy was reported as fusiform sarcoma. Extensive clinical examination, followed by full body CT sc…
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Pneumothorax in active pulmonary tuberculosis: resurgence of an old complicat…
With the recent resurgence of tuberculosis (TB) in western countries, the incidence of complicating secondary pneumothorax has also increased. The work-up and management of this complication differs from that in other types of secondary spontaneous pneumothorax (SSP).
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Editorial : How Best to Resuscitate Patients With Septic Shock?
What is the best approach for resuscitation of a patien twit hseptic shock? Despite considerable investigation over several decades, this important question still has no clear answer. There is agreement that resuscitation should proceed quickly, for the longer the delay, the greater the physiologic stress and endorgan injury. However, treatment options are principally intravenous fluids and va…
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BOOK REVIEW : Disease-related Malnutrition: An Evidence-based Approach to Tre…
Whoever cares for cost–benefit and cost–effectiveness of treatments must use this book; its focus is to establish, share with the readers and entice them to practice, adequate evidence-base for the provision of nutritional therapy
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Dynamic Changes in the ST-T Segment During Sleep in Ischemic Heart Disease
The electrocardiographic pattern during sleep was recorded in 140 patients with chronic ischemic heart disease by the Holter continuous recording system. Among the 97 patients who had fixed abnormal ST-T changes during the day, the severity of the pathologic pattern decreased during sleep in 39, remained unchanged in 35 and became more marked in 23 patients. The deterioration of ST-T changes i…
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Practical Genetics : Tuberous sclerosis
Tuberous sclerosis is a serious inherited disease which poses major challenges for affected families and those caring for them. Identification of the genes causing the condition and study of their protein products has shed light on the pathogenesis of the disease and provided valuable new information about signalling pathways regulating protein synthesis and cell growth. There is now the exciti…
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Tuberous sclerosis
Tuberous sclerosis is an autosomal dominant multisystemic genetic condition that can affect many organs: brain, skin, eye, heart, lungs and the kidney. It affects one in 7 to 8,000 people. Its main complications involve the nervous system (convulsions, intracranial hypertension), the kidneys (rupture of cysts and angiomyolipomas) and the lungs of adult females (rupture of bullae with lymphangio…
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Tuberous Sclerosis
Tuberous sclerosis or Tuberous Sclerosis Complex (TSC) is a genetic disorder characterized by the growth of numerous benign tumours in many parts of the body caused by mutations on either of two genes, TSC1 and TSC2. The case of a 31 year old female who fulfilled 8 major criteria of Tuberous Sclerosis Complex is reported. Multiple research work projects are being carried out on this disease, u…
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