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Recent advances in pediatric oncology
Newadvances in the field of pediatric oncology have had a tremendous impact on our approach to the diagnosis and treatment of childhood cancer over the past decade. This exciting era of discovery holds great promise for the successful treatment of an increasing number of heretofore incurable childhood cancers. Targeting molecular aberrations in tumors and/or modulating the immune system to max…
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Massive hemoptysis due to recurrence of bronchial to pulmonary vascular malfo…
Bronchial dieulafoy lesions are quite rare with relatively few case reports in the literature. Symptoms may vary but the lesion is often associated with hemoptysis and may present as massive hemoptysis. We present a case of a 69-year-old male with a recurrent episode of hemoptysis three years after treatment for a bronchial dieulafoy lesion. The bronchoscopy done three years prior during an ini…
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Evaluation of New Technologies in Gastrointestinal Endoscopy
Gastrointestinal (GI) tumors are the most commonly diagnosed cancers worldwide and the second leading cause of cancer-related death. Endoscopy is the gold standard for diagnosis of GI cancers. Early diagnosis of GI tumors by endoscopy at the precancerous or early stage may decrease the prevalence and mortality rate of GI cancers. The preventive role of endoscopic interventions and the limitatio…
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Serum Levels of FGF21 and Prediction of Cardiovascular Events
Over the last decade, the discovery of endocrine fibroblast growth factors (eFGFs) and their signaling pathways with regulatory functions in cell metabolism, but not proliferation, is among the major breakthroughs in the field of endocrinology and metabolism [1, 2]. Among eFGFs, FGF21 has attracted much attention as a potential pharmacotherapy against major metabolic diseases, such as obesity, …
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Risk of Hospitalization for Cardiovascular Events with b-Blockers in Hyperten…
Incident nebivolol, atenolol, or metoprolol monotherapy users with hypertension were identified using US claims data (2007–2014). The first b-blocker claim on/after 1/1/2008 defined the index drug/date. Hypertensive patients without pre-index cardiovascular history were followed until index drug discontinuation ([90 day supply gap), use of other b-blockers, or end of continuous plan enrollment
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Cardiovascular Complications of Marijuana and Related Substances: A Review
The recreational use of cannabis has sharply increased in recent years in parallel with its legalization and decriminalization in several countries. Commonly, the traditional cannabis has been replaced by potent synthetic cannabinoids and cannabimimetics in various forms. Despite overwhelming public perception of the safety of these substances, an increasing number of serious cardiovascular adv…
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Evidence-based management of gastrointestinal diseases
This special issue of Gastroenterology Report is directed at “Evidence-based management of gastrointestinal (GI) diseases”. Gastroenterologists are now using a range of diagnostic tests and therapies that were largely unavailable twenty years ago. Ours is a fast-moving field, with innovations being developed at a rapid pace
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A Randomized Trial of Central Venous Catheter Type and Thrombosis in Critical…
Observational studies suggest peripherally inserted central venous catheters (PICCs) are associated with a high risk of catheter-related large vein thrombosis (CRLVT) in critically ill neurologic patients. We evaluated the difference in thrombosis risk between PICCs and centrally inserted central venous catheters (CICVCs).
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ASCENDing to New Heights in Our Understanding of the Treatment of Depression …
Depression is the most common psychiatric condition among patients receiving maintenance hemodialysis. Depression negatively affects functional status and quality of life and is associated with increased treatment nonadherence, hospitalizations, and mortality (1). Despite the clinical and patient-reported significance of depression, clinicians often underrecognize and undertreat depressive symp…
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Fetomaternal Outcome in Medically Indicated Induction of Labour at Term Gesta…
It was a retrospective observational study and manual and electronic data were retrieved from a tertiary care centre of Southern India. All women after 37th week of gestation with single live fetus in cephalic presentation with a Bishop score
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