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Incidence of autoimmune diseases in a nationwide HIV/AIDS patient cohort in T…
It is not known if the incidences of autoimmune diseases are higher in individuals living with HIV infection or AIDS. Our study investigated the incidences of autoimmune diseases among people living with HIV/AIDS (PLWHA) in Taiwan during 2000–2012
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Massive hemoptysis from Rasmussen's aneurysm in active pulmonary tuberculosis…
Rasmussen’s aneurysm, a very rare complication of active pulmonary tuberculosis (TB), is a pulmonary artery aneurysm adjacent to or within a tuberculous cavity. It may lead to rupture and life threatening massive hemoptysis, an uncommon but challenging medico-surgical emergency. This complication warrants attention in view of the resurgence of tuberculosis and increasing occurrence of mult…
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Does dexmedetomidine offer brain protection?
Since the introduction of dexmedetomidine into clinical practice, the potent alpha2 agonist has been used in a variety of settings and for an increasing number of indications. The drug is a selective agonist to the alpha2-adreno-receptor subtype (alpha2-AR ). The alpha2-AR is widely distributed in the nervous system and in most peripheral tissues.
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Interventions to prevent hemodynamic instability during renal replacement the…
Hemodynamic instability related to renal replacement therapy (HIRRT) may increase the risk of death and limit renal recovery. Studies in end-stage renal disease populations on maintenance hemodialysis suggest that some renal replacement therapy (RRT)-related interventions (e.g., cool dialysate) may reduce the occurrence of HIRRT, but less is known about interventions to prevent HIRRT in critica…
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Amiodarone or Lidocaine for cardiac arrest: a systematic review and meta-anal…
Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lidocaine may be used if amiodarone is not available. Recent underpowered evidence suggests that amiodarone, lidocaine or placebo are equivalent with respect to survival at hospital discharge, but amiodarone and lidocaine showed higher hospital admission rates. We undertook a s…
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Pre- and post-treatment with amiodarone for elective electrical cardioversion…
Clinicians pre-treat patients with amiodarone to increase the efficacy of electrical cardioversion for atrial fibrillation (AF). We conducted a systematic review and meta-analysis of randomized controlled trials comparing pre- and post-treatment for electrical cardioversion with amiodarone versus no therapy on (i) acute restoration and (ii) maintenance of sinus rhythm after 1 year. We searched …
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Nutrition and chronic kidney disease
The incidence of malnutrition disorders in chronic kidney disease (CKD) appears unchanged over time, whereas patient-care and dialysis techniques continue to progress. Despite some evidence for cost-effective treatments, there are numerous caveats to applying these research findings on a daily care basis. There is a sustained generation of data confirming metabolic improvement when patients con…
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Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment an…
Almost one million (951 600) new cases of gastric cancer were diagnosed globally in 2012, resulting in ∼723 100 deaths [1]. Of these ∼140 000 cases and ∼107 000 deaths occurred in Europe [2]. Gastric cancer displays significant global variation in incidence; the highest rates are seen in Eastern Asia, Eastern Europe and South America, with lower rates in North America and Western Europe…
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Levobupivacaine for labor analgesia
Combined spinal‑epidural analgesia has become the preferred technique for labor analgesia as it combines the benefits of both spinal analgesia and flexibility of epidural catheter. Study was carried out with the primary aim to compare levobupivacaine and ropivacaine with fentanyl in terms of onset and duration of sensory block and to know maternal and fetal outcome
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Dose-Response Curves for Intrathecal Bupivacaine, Levobupivacaine, and Ropiva…
Bupivacaine, levobupivacaine, and ropivacaine are often given intrathecally for labor analgesia, but limited data are available for their dose-response properties in this context. The objective of this study was to describe the dose-response curves of these local anesthetics when given intrathecally for labor analgesia, to determine values for D50 (dose producing a 50% response) and to compare …
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