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Diphtheria: Clinical Manifestations, Diagnosis, and Role of ImmunizationIn Pr…
Diphtheria outbreaks, though very rare, still occur worldwide, in the developed and developing countries. Diphtheria has high mortality in non-vaccinated populations. Corynebacterium diphtheria produce very potent toxin when infected with a bacteriophage that migrates the toxin-encoding genetic elements into bacteria. The R domain binds to a cell surface receptor, permitting the toxin to ent…
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CUTANEOUS DIPHTHERIA WITH TOXIC MYOCARDITIS: REPORT OF FATAL CASE WITH NECROP…
IN the surgery of war wounds, one must expect to lose a number of patients whose injuries are extensive. However, when the injury is in itself trivial and a fatal complication results, the outcome is apt to disturb the equanimity of those who have attended the case and to point the moral that there are no trivial war wounds. Every case is potentially serious and the results unpredictable.
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Clinical spectrum and outcomes of pediatric diphtheria
The clinical spectrum and outcomes of pediatric diphtheria in this study are relatively similar to reports from other hospitals. Mortality was mostly in patients who lack basic or booster immunizations, are poorly nourished, or have bull neck, myocarditis, or hospital stays < 5 days
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Inhaled nitric oxide in adult patients with acute respiratory distress syndrome
In some patients, acute respiratory distress syndrome (ARDS) leads to life-threatening refractory hypoxemia developing. Physicians may consider hypoxemic rescue therapies in an attempt to improve oxygenation in these patients while on conventional mechanical ventilation support. Use of inhaled nitric oxide (iNO) in ARDS is one of the most widely-studied pharmacological interventions over the pa…
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An Introduction to Nitric Oxide Sensing and Response in Bacteria
Nitric oxide (NO) is a radical gas that has been intensively studied for its role as a bacteriostatic agent. NO reacts in complex ways with biological molecules, especially metal centers and other radicals, to generate other bioactive compounds that inhibit enzymes, oxidize macromolecules, and arrest bacterial growth. Bacteria encounter not only NO derived from the host during infection but al…
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Age and aphasia: a review of presence, type, recovery and clinical outcomes
1617 articles were identified during the initial search. Forty studies including 14,795 study participants were included in the review. The review generally demonstrated that: (a) stroke patients with aphasia are typically older than stroke with patients without aphasia and (b) aphasia type and age are associated as younger patients with aphasia are more likely to exhibit non-fluent or Broca’…
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Short-Term Memory and Aphasia: From Theory to Treatment
This article reviews existing research on the interactions between verbal short-term memory and language processing impairments in aphasia. Theoretical models of short-term memory are reviewed, starting with a model assuming a separation between short-term memory and language, and progressing to models that view verbal short-term memory as a cognitive requirement of language processing. The rev…
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Home-based therapy for chronic Wernicke’s aphasia
Many stroke survivors experience language impairments (aphasia) beyond 6 months to 1 year after the stroke. Language is a fundamental element in human interaction, and aphasia is independently associated with less participation in rehabilitation programmes, depression and worse quality of life
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Viral Hepatitis in Pregnancy – A study of its Effect on Maternal and Foetal…
The outcome of Hepatitis during pregnancy has been observed to be widely different by various authors, ranging from the benign to fatal. A poor outcome has increasingly been observed in pregnant women suffering from Hepatitis in Central India. Hence, this study was undertaken to study the incidence, causative organisms and chief prognostic factors affecting the outcome of viral hepatitis in pre…
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Metformin inhibits hepatitis B virus protein production and replication in hu…
Hepatitis B virus surface antigen (HBsAg) plays an important role in maintaining the tolerance and may interfere with host innate and adaptive immune responses; therefore, novel therapeutic strategies to reduce HBsAg loads in patients infected with hepatitis B virus (HBV) are emerging as an attractive but challenging issue. Metformin could regulate hepatic metabolism while the latter interacts …
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