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Spontaneous Bacterial Peritonitis: Pathogenesis, Diagnosis, Treatment
Due to inadequate defence mechanisms, cirrhotic patients with ascites have an increased susceptibility to infections, the most frequent and the most severe one being spontaneous bacterial peritonitis (SBP). SBP diagnosis is based on testing of the ascitic fluid obtained by paracentesis. A polymorphonuclear cell count of more than 250 cells/mm3 of ascitic fluid is considered diagnostic and from …
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Spontaneous bacterial peritonitis
A 38-year-old man with end-stage liver disease secondary to chronic hepatitis C infection, who had been evaluated and listed for a liver transplantation, presented with substantial ascites necessitating several abdominal paracenteses. He had a history of spontaneous bacterial peritonitis, small bowel obstructions, and weight loss. In the 3 years he had been on the waiting list he had several…
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Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is probably the best-characterized infectious complication that develops in patients with cirrhosis and ascites [1, 2]. Since its first description in 1964, a large body of knowledge has accumulated regarding the clinical presentation, diagnosis, pathogenesis, treatment and prevention of SBP, and the prognosis of patients who develop this infection [1–3].
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Antidiabetic effects of fermented soybean products on type 2 diabetes
Historically, the incidence of type 2 diabetes has been lower in Asian populations compared with those in Western countries. One possible reason for the lower incidence among Asians is that they consume fermented soybean products, which are unique to the traditional Asian diet. Some have hypothesized that dietary phytoestrogens and soy peptides in fermented soybean foods consumed in traditi…
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The soy isoflavone genistein reverses oxidative and inflammatory state, neuro…
Treatment of diabetes complications remains a substantial challenge. The aim of this study was to explore the ability of the soy isoflavone genistein in attenuating the signs that follow diabetes onset: nociceptive hypersensitivity, oxidative and inflammatory state,nerve growth factor(NGF)decrease and vascular dysfunctions. Genistein (3 and 6 mg/kg) was administered to C57BL/6J streptozotoci…
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The protective effects of dexmedetomidine on ischemic brain injury: A meta-an…
Intracranial lesions, traumaor surgery-related damage activate immune inflammation and neuroendocrine responses, causing ischemic brain injury. Studies have shown that inflammatory cascade mediated by neuroendocrine hormones and proinflammatory mediators is implicated in the pathophysiology of ischemic brain injury. Alpha2-adrenoceptor agonists, dexmedetomidine, is widely used as neuroprotec…
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Discovery and Validation of a Molecular Signature for the Noninvasive Diagnos…
In the discovery set, urinary cell levels of the following mRNAs were significantly associated with the presence of allograft fibrosis: vimentin (PG0.0001, logistic regression model), hepatocyte growth factor (PG0.0001), >Ysmooth muscle actin (PG0.0001), fibronectin 1 (PG0.0001), perforin (P=0.0002), plasminogen activator inhibitor 1 (P=0.0002), transforming growth factor A1 (P=0.0004), tiss…
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Respiratory viruses in returning Hajj & Umrah pilgrims with acute respiratory…
Respiratory tract infections are common among Hajj and Umrah pilgrims which pose a public health risk of spread of respiratory infections. Influenza has been reported from Indian Hajj and Umrah returning pilgrims, but data on other respiratory pathogens are sparse in India. Here we report the presence of common respiratory viral pathogens in returning Hajj and Umrah pilgrims suffering from ac…
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Pulmonary Rehabilitation in lung cancer
Non-small-cell lung cancer (NSCLC) represents a very severe disease, being its incidence increasingly reported and, nowadays, successfully treatable only when surgery is deemed to be feasible. Furthermore, the disease and the clinical effects related to the complementary therapies (radio and/or chemotherapy) may strongly affect, frequently with dramatic clinical side effects, the patient’s ab…
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Impact of pulmonary rehabilitation on postoperative complications in patients…
Given the extent of the surgical indications for pulmonary lobectomy in breathless patients, preoperative care and evaluation of pulmonary function are increasingly necessary. The aim of this study was to assess the contribution of preoperative pulmonary rehabilitation (PR) for reducing the incidence of postoperative pulmonary complications in non-small cell lung cancer (NSCLC) patients with c…
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