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Chronic kidney disease in pregnancy: Maternal and fetal outcomes and progress…
Of the 55 pregnancies, 71% experienced pre-term delivery, 38% had intra-uterine growth restriction and 62% required caesarean section. Of all, 60% of neonates required neonatal intensive care unit (NICU) admission and six perinatal deaths occurred. Of all, 67% of women suffered preeclampsia, 47% anaemia and 3 patients required dialysis in pregnancy. Postpartum deterioration of renal function oc…
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Nasal High‑flow Therapy in Infants and Children
This review highlights and summarizes the current evidence and knowledge of nasal high flow therapy management in infants and children. This review outlines the distinct differences in the use of NHF therapy between children and adults. A comprehensive literature review has been performed reviewing the relevant physiological studies and current evidence of support measures in these children.…
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Spectrum of illness among returned Australian travellers from Bali, Indonesia…
Bali, Indonesia, presents significant infectious and non-infectious health risks for Australian travellers. Understanding this spectrum of illnesses has the potential to assist clinicians in evaluating unwell returning travellers and guide provision of pre-travel advice
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Angiotensin II and skeletal muscle abnormalities
The renin–angiotensin system (RAS) is known to be activated systemically and in local organs in cardiovascular disease, metabolic disease and other chronic diseases, as well as with age. This activation is strongly associated with organ damage. Many studies have reported the role of RAS activation in cardiovascular disease, and angiotensin II (Ang II) in particular has been identified as a…
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Clinical Experience With IV Angiotensin II Administration: A Systematic Revie…
Adverse events associated with angiotensin II were infrequent; however, exacerbation of asthma and congestive heart failure and one fatal cerebral hemorrhage were reported. This systematic review supports the notion that angiotensin II has an acceptable safety profile for use in humans
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Epidemiology and Prognosis of Paraneoplastic Syndromes in Hepatocellular Carc…
Paraneoplastic syndromes (PNS) such as hypercalcaemia, hypercholesterolaemia, and erythrocytosis have been described in hepatocellular carcinoma (HCC). Aims. (1) To examine the prevalence, clinical characteristics, and survival of PNS in HCC patients and (2) to evaluate the extent to which each individual PNS impacts on patient survival
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Guidelines for the Diagnosis and Management of Gastroesophageal Refl ux Disease
Gastroesophageal refl ux disease (GERD) is arguably the most common disease encountered by the gastroenterologist. It is equally likely that the primary care providers will fi nd that complaints related to refl ux disease constitute a large proportion of their practice. Th e following guideline will provide an overview of GERD and its presentation, and recommendations for the approach to dia…
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The Relationship Between Slow Coronary Flow and Angiotensin Converting Enzyme…
Endothelial dysfunction in coronary arteries is the main pathogenetic mechanism in patients with slow coronary flow (SCF). Angiotensin converting enzyme (ACE) gene polymorphism has important effects on endothelial function. However, angiographic studies investigating the relation between the ACE and angiotensin II type 1 receptor (ATIIR1) insertion (I)/deletion (D) polymorphism and SCF is…
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Surgical management of advanced non-small cell lung cancer
More than 75% of the cases of non-small cell lung cancer (NSCLC) are diagnosed in advanced stages (IIIA-IV). Although in these patients the role of surgery is unclear, complete tumor resection can be achieved in selected cases, with good long-term survival. In this review, current indications for surgery in advanced NSCLC are discussed. In stage IIIA (N2), surgery after induction chemotherap…
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Long-term outcomes of surgical resection for stage IV non-small-cell lung can…
Surgery for cT1-2, N0-1, M1 or cT3, N0, M1 disease is associated with a 5-year survival of 25% and does not appear to compromise outcomes when compared to non-operative therapy, supporting guidelines that recommend surgery for very select patients with stage IV disease. However, surgery provides less benefit and should be considered much less often for stage IV patients with mediastinal noda…
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