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In the Clinic® Herpes Zoster
Primary care providers and hospitalists frequently encounter older or immunocompromised patientswith herpes zoster accompanied by debilitating pain. Atypical presentations and zosteriform herpes simplex may present diagnostic challenges to clinicians. This article summarizes the background, evidence, and guidelines for the diagnosis, complications, treatment, and prevention of herpes zoster.
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Online Resources in Plastic Surgery Education: A Toolbox for Modern Trainees …
Plastic surgery is a rapidly evolving field that requires novel approaches in providing continuous and dynamic educational resources to address the increasing time and skill demands from residents. Online resources in their various forms, such as books, journals, simulators, and applications, are increasingly used by residents, notably over traditional print and in-person counterparts
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Fluid Resuscitation In Patients With End-Stage Renal Disease Presenting With …
In the United states 750,000 patients are diagnosed with severe sepsis every year with an average annual increase of 13.0%. Septic patients with End Stage Renal Disease (ESRD) have 100-300 fold increased mortality when compared to the general population. There has been a plethora of information about the use of fluid resuscitation in sepsis. However, there is sparse information about the use of…
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Fluid Resuscitation And Mortality In Sepsis With End-Stage Renal Disease
Patients with end-stage renal disease on dialysis (ESRD-HD) have an increased risk of sepsis and sepsis-related mortality. Professional society and government guidelines recommend weight-based initial IV fluid resuscitation targets as part of sepsis care bundles; however, there are no specific recommendations for patients with sepsis and ESRD-HD. While higher volumes of administered fluids have…
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The Renin-Angiotensin System and Progression of Renal Disease: From Hemodynam…
The renal community is faced with an ever increasing number of patients reaching end-stage renal failure. Clinical studies have provided clear evidence that angiotensin-converting enzyme (ACE) inhibitors, and probably also AT1 receptor antagonists, at least in patients suffering from type 2 diabetes, slow disease progression to end-stage renal failure.
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Renin-Angiotensin-Aldosterone System and Progression of Renal Disease
Inhibition of the renin-angiotensin-aldosterone system (RAAS) is one of the most powerful maneuvers to slow progression of renal disease. Angiotensin II (AngII) has emerged in the past decade as a multifunctional cytokine that exhibits many nonhemodynamic properties, such as acting as a growth factor and profibrogenic cytokine, and even having proinflammatory properties. Many of these delete…
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Role of the intrarenal renin–angiotensin system in the progression of renal…
The intrarenal renin–angiotensin system (RAS) has many well-documented pathophysiologic functions in both blood pressure regulation and renal disease development. Angiotensin II (Ang II) is the major bioactive product of the RAS. It induces inflammation, renal cell growth, mitogenesis, apoptosis, migration, and differentiation
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The genes involved in asthma with the treatment of human embryonic stem cell-…
Asthma is affecting more than 300 million people worldwide, which represents the most common chronic disease among children. We previously found that mesenchymal stem cells (MSCs) derived from induced pluripotent stem cells (iPSCs) modulated the immune response on Th2-mediated asthma in vivo and in vitro. This study further evaluated the immunomodulatory effects of MSCs from human embryonic …
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Recommendations for radiological diagnosis and assessment of treatment respon…
The last decade has seen substantial progress in the diagnostic and therapeutic approach to lung cancer, thus meaning that its prognosis has improved. The Spanish Society of Medical Radiology and the Spanish Society of Medical Oncology have therefore produced a national consensus statement to make recommendations for radiological diagnosis and assessment of treatment response in patients with l…
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Characteristics and Trends of Pneumoconiosis in the Jiangsu Province, China, …
This study aims to describe the characteristics and trends of pneumoconiosis in the Jiangsu Province, China, and provide information for the occupational diseases control. We collected and analyzed the data of pneumoconiosis cases reported annually from 2006 to 2017. The information of the cases mainly includes case distributions, clinical types and stages, enterprise types and scales, as well …
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