Intracranial aneurysms can occur in patients with brain arteriovenous malformations (AVMs), and this not uncommon association poses important therapeutic challenges. In patients presenting with intracranial hemorrhage, the AVM is responsible for bleeding in 93% of cases, with the remaining 7% related to associated intracranial aneurysms
Acute ischemic stroke is a major cause of mortality and morbidity in the United States.We review the latest data and evidence supporting catheter-directed treatment for proximal artery occlusion as an adjunct to intravenous thrombolysis in patients with acute stroke.
The most common causes of acute pancreatitis (AP) are biliary tract diseases with cholestasis and alcohol consumption. In 10%–15% of patients, etiology determination is difficult. Identification of the etiology allows for the implementation of adequate treatment. The aim of this study was to assess the utility of the serum concentrations of total bile acids (TBA) to diagnose AP etiology in th…
Cholestasis (slowing of bile flow) may be acute or chronic and affect any age group. In infants and children the causes often are congenital or inherited and as a result of improved management some affected children now survive to adulthood. Although jaundice is a hallmark of cholestasis it may be absent, particularly in adults with chronic cholestatic liver disease most of whom are entirely as…
The criterion of total bile acid (TBA) concentration for the diagnosis of intrahepatic cholestasis in pregnant women remains debated. The purpose of this study was to establish a reference range of TBA concentration in Chinese pregnant women. Clinical data of Chinese women aged > 18 years with singleton pregnancy were retrospectively analyzed. The blood samples were collected during pregnancy a…
Ultrasound and liver function tests (serum bilirubin and serum alkaline phosphatase) are used as screening tests for the diagnosis of common bile duct stones in people suspected of having common bile duct stones. There has been no systematic review of the iagnostic accuracy of ultrasound and liver function tests
Acne is one of the most common disorders treated by dermatologists and other health care providers. While it most often affects adolescents, it is not uncommon in adults and can also be seen in children. This evidence-based guideline addresses important clinical questions that arise in its management. Issues from grading of acne to the topical and systemic management of the disease are reviewe…
Acne vulgaris is the most common skin disorder encountered in dermatology practice in the United States, affecting approximately 85 percent of teenagers and sometimes persisting into and throughout adulthood. Although not life-threatening, acne can have a significant adverse psychological and physical impact. Many patients with acne report feelings of depression, anxiety, emotional stress, or …
Oral antibiotics have been used for the treatment of acne vulgaris for six decades. Among dermatologists, tetracyclines represent at least three-fourths of the oral antibiotics prescribed in clinical practice. Unlike other specialties, antibiotic use in dermatology is predominantly for the treatment of noninfectious disorders, such as acne vulgaris and rosacea, which usually involves prolonged …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pandemic. Safe and effective vaccines are needed urgently.