The essential of tobacco use is nicotine dependence. It is important to understand that habitual smoking is a chronic dependency that is liable to relapse but is amenable to repeated treatment, and to incorporate the treatment of this dependency into the routine healthcare activities. The efficacy of therapeutic programs that deal with smoking cessation on the basis of approaches using behavio…
There are now more former cigarette smokers than current smokers in the United States (U.S. Department of Health and Human Services [USDHHS] 2014). For more than a decade, national surveillance data on smoking cessation have revealed a similar pattern, with modest improvement—two-thirds of adult cigarette smokers indicate a desire to quit, and just over half try to quit each year; however, l…
Smoking is the leading preventable cause of morbidity and mortality worldwide. Cessation of smoking significantly reduces the risk of dying from tobacco‑related diseases such as oral cancer, heart diseases, and lung cancer. Since smoking is considered to be a major health hazard in the world, dentists and health‑care workers need to consider it seriously and assist their patients in smoking…
To determine whether the virtual reality as a distracting intervention could reduce pain and fear in school-age children receiving intravenous injections at an emergency department
Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily practice. However, the final decisions concerning an individual patient must be made by the…
Cardiovascular disease remains the principal cause of death and disability among patients with diabetes mellitus. Diabetes exacerbates mechanisms underlying atherosclerosis and heart failure. Unfortunately, these mechanisms are not adequately modulated by therapeutic strategies focusing solely on optimal glycemic control with currently available drugs or approaches. In the setting of multi-fact…
Diabetes mellitus is a risk factor for cardiovascular disease (CVD) and has been associated with 2- to 4-fold higher mortality. Diabetes mellitus–related mortality has not been reassessed in individuals receiving routine care in the United States in the contemporary era of CVD risk reduction
Ischemic complications are a common cause of neurological deficits following low-grade glioma (LGG) surgeries. In this study, the authors evaluated the incidence, risk factors, and long-term implications of intraoperative ischemic events.
Mechanical thrombectomy is the established treatment for acute ischemic stroke due to large vessel occlusion (LVO). The authors sought to identify early predictors of a favorable outcome in stroke patients treated with mechanical thrombectomy
There are no effective therapeutic drugs for cerebral aneurysms, partly because the pathogenesis remains unresolved. Chronic inflammation of the cerebral arterial wall plays an important role in aneurysm formation, but it is not clear what triggers the inflammation. The authors have observed that vascular endothelial P2X4 purinoceptor is involved in flow-sensitive mechanisms that regulate vascu…