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Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a…
Gouty arthritis is uncommon in childhood and adolescence. On the other hand, there has been no report of cases with development of gouty arthritis with post-streptococcal acute glomerulonephritis (PSAGN) in pediatric patients. Here we report the case of a mildly obese 12-year-old boy with PSAGN complicated by gouty arthritis of the left first metatarsophalangeal joint. On follow-up, it was conf…
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Post-streptococcal glomerulonephritis leading to posterior reversible encepha…
Posterior reversible encephalopathy syndrome is a clinical radiographic syndrome of heterogeneous etiologies. Developing hypertensive encephalopathy following post-streptococcal glomerulonephritis is a known but uncommon manifestation and developing posterior reversible encephalopathy syndrome in such a situation is very rare. We report a case with contrast-enhanced computed tomography and m…
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Post-Streptococcal Glomerulonephritis in Two Patients Following Deceased Dono…
Post-streptococcal glomerulonephritis (PSGN) is a well-known cause of renal injury. This disease is caused by a prior infection with specific nephritogenic strains of group A beta-hemolytic streptococcus resulting in formation of immune complexes in the glomeruli. Clinical presentation can range from asymptomatic, microscopic hematuria to the nephritic syndrome which is defined by red to brown …
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Current Concepts of Premature Ventricular Contractions
Premature ventricular contractions (PVCs) are early depolarizations of the myocardium originating in the ventricle. PVCs are common with an estimated prevalence of 40% to 75% in the general population on 24- to 48-hour Holter monitoring. Traditionally, they have been thought to be relatively benign in the absence of structural heart disease but they represent increased risk of sudden death i…
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Premature Ventricular Contraction Coupling Interval Variability Destabilizes …
Variability in premature ventricular contraction (PVC) coupling interval (CI) increases the risk of cardiomyopathy and sudden death. The autonomic nervous system regulates cardiac electrical and mechanical indices, and its dysregulation plays an important role in cardiac disease pathogenesis. The impact of PVCs on the intrinsic cardiac nervous system (ICNS), a neural network on the heart, remai…
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Bridging the Great Divide: What Can Neurology Learn from Psychiatry?
Neurology and psychiatry share common historical origins and rely on similar tools to study brain disorders. Yet, the practical integration of medical and scientific approaches across these clinical neurosciences has remained elusive. While much has been written about the need to incorporate emerging systems-level, cellular-molecular and genetic-epigenetic advances into a science of mind for ps…
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Curriculum in Psychiatry and Neurology for Pharmacy Programs
To describe pharmacy curricula in psychiatry and neurology and to report on neuropsychiatric pharmacy specialists’ views on optimal curriculum
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Atrial Fibrillation and Mechanisms of Stroke: Time for a New Model
Thirty-three million people have atrial fibrillation (AF), a disorder of heart rhythm.1 Over the past several decades, we have learned that this dysrhythmia originates in the interplay between genetic predisposition, ectopic electrical activity, and abnormal atrial tissue substrate and then feeds back to remodel and worsen tissue substrate and, thereby, propagates itself.
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Silent Cerebral Embolism during Atrial Fibrillation Ablation: Pathophysiology…
Although many efforts have been directed to improve atrial fibrillation transcatheter ablation safety, thromboembolism to the brain remains one of the major complications. In fact several studies have confirmed occurrence of silent cerebral embolic lesions by post-procedure magnetic resonance imaging, the present review will focus on the possible mechanisms leading to silent cerebral embolism i…
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Analysis of Infusion Patterns of Propofol and Remifentanil During Rigid Bronc…
We analyzed the dosage pattern of anesthetic drugs administered to maintain anesthesia during rigid bronchoscopy
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