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Anxiety and Salivary Cortisol Levels in Children Undergoing Esophago-Gastro-D…
Esophagogastroduodenoscopy (EGD) can cause fear and anxiety in children. Cortisol, which is the most important glucocorticoid hormone in humans, can increase under physiological stress. The purpose of this study was to measure the salivary cortisol level (SCL) and anxiety level in patients undergoing EGD and evaluate their effects on the procedure.
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Clinical Practice Guideline for the Diagnosis and Treatment of Pediatric Obesity
The following areas were systematically reviewed, especially on the basis of all available references published in South Korea and worldwide, and new guidelines were established in each area with the strength of recommendations based on the levels of evidence: 1) definition and diagnosis of overweight and obesity in children and adolescents; 2) principles of treatment of pediatric obesity; 3)…
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The Frailty Syndrome : Definition and Natural Hystory.
Frailty is a common clinical syndrome in older adults, which carries an increased risk for poor health outcomes, including falls, incident disability, hospitalization, and mortality. Elucidating its cause and natural history is therefore critical for identifying high-risk subsets and new arenas for frailty prevention and treatment
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Effect Initial Heart rate Cardiac Troponin & Ejection Fraction on patients wi…
Increased heart rate has shown to be associated with adverse cardiovascular outcomes. This aim of this study was to find the association of troponin level and ejection fraction (EF) with triage heart rate in patients with non-ST elevation myocardial infarction (NSTEMI). It was hypothesized that heart rate at triage will be independently associated with higher troponin level and lower EF after N…
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Safety and Success of Vaginal Birth after Caesarian Delivery in Patient with …
The objective of this study was to determine if preeclampsia (PRE) or gestational hypertension (GH) affects the rate of success of vaginal birth after cesarean delivery (VBAC), VBAC-related complications, or patient election to attempt VBAC. We performed a retrospective cohort study of all women who were offered VBAC from 1996 to 2000 in 17 community and university hospitals
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Diagnosis and Treatment Extrapulmonary TB
Extrapulmonary tuberculosis (EPTB) constitutes about 20% of all cases of tuberculosis (TB) in Korea. Diagnosing EPTB remains challenging because clinical samples obtained from relatively inaccessible sites may be paucibacillary, thus decreasing the sensitivity of diagnostic tests. Whenever practical, every effort should be made to obtain appropriate specimens for both mycobacteriologic and hist…
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Spironolactone vs placebo, Bisoprolol, and Doxazin to Determine the Optimal T…
Optimal drug treatment for patients with resistant hypertension is undefi ned. We aimed to test the hypotheses that resistant hypertension is most often caused by excessive sodium retention, and that spironolactone would therefore be superior to non-diuretic add-on drugs at lowering blood pressure.
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International Consensus on Risk Management of Diabetic Ketoacidosis in Patien…
Sodium glucose cotransporter (SGLT) inhibitors are new oral antidiabetic medications shown to effectively reduce glycated hemoglobin (A1C) and glycemic variability, blood pressure and bodyrnweight without intrinsic properties to cause hypoglycemia in people with type 1 diabetes
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Ambroxol Effects in Glucocerebrosidase and a-Synuclein Transgenic Mice
Gaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase. Both homozygous and heterozygous glucocerebrosidase 1 mutations confer an increased risk for developing Parkinson disease. Current estimates indicate that 10 to 25% of Parkinson patients carry glucocerebrosidase 1 mutations. Ambroxol is a small molecule c…
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Systematic Review of Group A Streptococcal emm Types Associated with Acute Po…
Acute post-streptococcal glomerulonephritis (APSGN) is a postinfectious immune-mediated kidney disease associated with group A Streptococcus (GAS). The prevalence of APSGN varies within and between countries and is influencedby socioeconomic, host, and bacterial factors. Thedisease ismoreprevalent in developing countries and resource-poor settings ofdeveloped countries, such as the Indigenou…
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