Obstetric hemorrhage in a case of hypertrophic obstructive cardiomyopathy wit…

The physiological changes occurring during pregnancy and labor may reveal or exacerbate the symptoms of hypertrophic obstructive cardiomyopathy (HOCM). The addition of obstetric hemorrhage to this presents a unique challenge to the anesthesiologists and intensivists managing these patients in the operation theatres and the Intensive Care Units. Here we present a case of HOCM with automatic impl…

EARLY FLUID RESUSCITATION OF END STAGE RENAL DISEASE PATIENTS WITH SEVERE SEP…

The Surviving Sepsis (SS) Guidelines recommend early, aggressive fluid resuscitation with 30mL/kg crystalloid for hypotension or lactate >4mmol/L within the first 3hours of suspected sepsis (t S-3). These guidelines are not always applied to septic patients with end stage renal disease (ESRD) due to fear of developing complications. We hypothesized that ESRD patients with severe sepsis (with h…

Metabolic syndrome : Consensus & Controversy : State of the Art

Metabolic syndrome is an epidemic that affects more and more people, increasing the probability of suffering metabolic and cardiovascular diseases in the short, medium or long term depending on the severity. The purpose of this article is to review the metabolic syndrome, assessing consensus, controversy and prevalence. The methodology was the preparation of a literature review on various healt…

The Impact of Vitamin D in the treatment of essential hypertension

The aim of this review is to investigate, whether there is a possible link between vitamin D supplementation and the reduction of blood pressure in hypertensive patients. The renin-angiotensin-aldosterone system is known for being deeply involved in cardiovascular tonus and blood pressure regulation. Hence, many of the pharmaceutical antihypertensive drugs inhibit this system. Interestingly, ex…

The Association between hypovitaminosis D and metabolic syndrome

The metabolic syndrome and its components have been associated with hypovitaminosis D in many observational trials. Several mechanisms have been proposed to explain this relationship and include most conditions that are present in patients with the metabolic syndrome. A causal relationship of the association between the metabolic syndrome and hypovitaminosis D, however, has not been demonstr…

Risk Factors and Stroke Characteristic in Patients with Postoperative Strokes

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Physical inactivity is a strong risk factor for stroke in the oldest old: Fin…

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Copeptin based approach Diabetes Insipidus

The indirect water-deprivation test is the current reference standard for the diagnosis of diabetes insipidus. However, it is technically cumbersome to administer, and the results are often inaccurate. The current study compared the indirect water-deprivation test with direct detection of plasma copeptin, a precursorderived surrogate of arginine vasopressin

Obesity-related heart failure with preserved ejection fraction: new treatment…

Obesity has risen in the US and worldwide, and has become a major risk factor for type 2 diabetes mellitus (T2DM), hypertension, cardiovascular disease, and heart failure (HF), mostly HF with preserved ejection fraction (HFpEF). Also, the prevalence of HF is quite high in the US accounting for 6.6 million adults at present and is projected to reach 8.5 million by the year 2030 and is equally di…

Thrombosis in pregnancy : update in diagnosis and management

Acute venous thromboembolism poses significant problems in pregnancy, a time when objective diagnosis and prompt treatment are essential. Events can occur at any stage in pregnancy, but the period of greatest risk is in the weeks after delivery. Ultrasound venography remains the diagnostic technique of choice for deep venous thrombosis. For pulmonary thromboembolism, ventilation perfusion lung…