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Pediatric Gastroenterology in Cuba: Evolution and Challenges
The professional practice of pediatric gastroenterology arose in Cuba as an expression of the specialty’s development internationally and Cuba’s new strategies in public health, and in response to national needs for health care expertise in digestive diseases of infants, older children and adolescents
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Anaesthesia for cancer patients
Cancer is beginning to outpace cardiovascular disease as the primary cause of death in the developed world. A majority of cancer patients will require anaesthesia either for primary debulking tumour removal or to treat an adverse consequence of the malignant process or its treatment
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Drugs of anaesthesia and cancer
Anaesthesia represents one of the most important medical advances in history,and,nowadays, can widely beconsidered safe,thanks to the discovery of new drugs and the adoption of modern technologies .Nevertheless,anaesthetic practices still represent cause for concern regarding the consequence sthey produce. Various anaesthetics are frequently used without knowing their effects on specific diseas…
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Gas exchange and ventilation–perfusion relationships in the lung
While the healthy lung efficiently exchanges respiratory gases, hypoxaemia and hypercapnia indicate pathophysiology and failure of the lung to provide adequate gas exchange. An understanding of how gases are transferred and the causes of inefficient gas exchange are central to caring for patients with lung diseases. In this article, we will review the normal and pathological mechanisms of ga…
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Diagnosing Bacterial Vaginosis with a Novel, Clinically-Actionable Molecular …
Bacterial vaginosis is a common condition among women of reproductive age and is associated with potentially serious side-effects, including an increased risk of preterm birth. Recent advancements in microbiome sequencing technologies have produced novel insights into the complicated mechanisms underlying bacterial vaginosis and have given rise to new methods of diagnosis
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Raynaud's Disease in Children
Six children with primary Raynaud's disease have been studied with plethysmography and multiple-site skin-temperature readings. All six were free of systemic disease. Each demonstrated the characteristic sequence of pallor, cyanosis, and rubor when subjected to generalized cold, but application of local cold produced only modest reduction in skin temperature and digital pulse. Only one child ha…
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Raynaud's disease
We report five children who presented with Raynaud's disease in whom we could find no clinical, haematological, or immunological evidence of a collagen disorder. Oral phenoxybenzamine proved useful for maintenance treatment in most, with infusions of prostacyclin, nitroprusside, and ketanserin during acute attacks
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Correlation of Bone Mineral Density Scores and Proton Pump Inhibitors Use in …
We aimed to identify any correlation between long-term proton pump inhibitor use and low bone mineral density in the elderly
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Bevacizumab prevents brain metastases formation in lung adenocarcinoma
Patients with non-squamous non-small cell lung cancer (nsNSCLC; largely lung adenocarcinoma) are at high risk of developing brain metastases. Preclinical data suggested that anti-VEGF-A therapy may prevent the formation of nsNSCLC brain metastases. Whether non-brain metastases are also prevented, and whether bevacizumab shows a brain metastases preventive activity in cancer patients is unknown.…
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Mesenchymal stem cells abrogate experimental asthma by altering dendritic cel…
Mesenchymal stem cells (MSCs) have been investigated in the treatment of numerous autoimmune diseases. However, the immune properties of MSCs on the development of asthma have remained to be fully elucidated. Airway dendritic cells (DCs) have an important role in the pathogenesis of allergic asthma, and disrupting their function may be a novel therapeutic approach. The present study used a mous…
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