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Interleukin-21 gene polymorphisms and chronic hepatitis B infection in a Chin…
In this case-control study, 366 Chinese HBV-infected patients were recruited and divided into hepatocellular carcinoma (HCC; n = 94) and non-HCC (n = 272) groups at The First Affiliated Hospital of Sun Yat-Sen University, from April 2009 to December 2012. In the non-HCC group, the patients were classified into three clinical subsets, 76 patients had chronic hepatitis B, 101 were HBV carriers a…
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Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators o…
Hepatitis B virus (HBV) generally causes self-limiting infection in immunocompetent adults, but establishes chronic infection in some adults and in most maternally infected infants. Factors determining clearance versus persistence are not fully understood. Hydrodynamic injection (HDI) of HBV replicon plasmid via tail vein generally results in quick clearance in immunocompetent adult mice. Here,…
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European Stroke Organization Guidelines for the Management of Intracranial A…
Intracranial aneurysm with and without sub-arachnoid haemorrhage (SAH) is a relevant health problem: The overall incidence is about 9 per 100,000 with a wide range, in some countries up to 20 per 100,000. Mortality rate with conservative treatment within the first months is 50–60%.
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Cerebrospinal Fluid Analysis
Lumbar puncture is frequently performed in primary care. Properly interpreted tests can make cerebrospinal fluid (CSF) a key tool in the diagnosis of a variety of diseases. Proper evaluation of CSF depends on knowing which tests to order, normal ranges for the patient’s age, and the test’s limitations. Protein level, opening pressure, and CSF-to-serum glucose ratio vary with age.
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Benign phyllodes tumours of the breast: (Over) Treatment of margins – a lit…
Phyllodes tumours form a small group of fibroepithelial breast lesions (2-3 %). They are classified as benign, borderline, or malignant. (1). Benign phyllodes tumours are the largest subgroup of phyllodes tumours (50 - 80%), (2) A margin of 1 cm has been suggested as standard of care for all groups of phyllodes tumours (3) (4) (5) (6).
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Penggunaan Antibiotik pada Terapi Demam Tifoid Anak di RSAB Harapan Kita
Insidens demam tifoid di Indonesia cukup tinggi (>100 kasus per 100.000 populasi per tahun). Insidens pada anak usia 3-6 tahun adalah 1307 per 100.000 populasi per tahun, dan 1172 pada usia 7-19 tahun. Chloramphenicol sampai saat ini masih merupakan obat pilihan lini pertama untuk terapi demam tifoid pada anak. Antibiotik lain yang dipergunakan untuk terapi demam tifoid anak adalah cotrimoxazo…
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PENGGUNAAN ANTIBIOTIKA PADA PASIEN ANAK PENDERITA TIFUS ABDOMINALIS DI INSTAL…
Tifus abdominalis merupakan penyakit infeksi sistemik dengan tingkat kematian yang signifikan terjadi hampir sepanjang tahun. Penyakit ini masih merupakan permasalahan kesehatan umum yang terjadi di negara-negara berkembang, terutama pada anak-anak di Indonesia. Tujuan penelitian ini adalah untuk mengetahui penggunaan antibiotika pada pasien anak penderita tifus abdominalis di instalasi rawat …
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Current concepts in severe acute and necrotizing pancreatitis: an evidence-ba…
The incidence of acute pancreatitis continues to rise, inducing substantial medical and social burden, with annual costs exceeding two billion dollars in the USA alone. Although the majority of patients develop mild pancreatitis, 20% develop severe and/or necrotizing pancreatitis, requiring advanced medical and interventional care. Morbidity resulting from local and systemic complications as w…
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Timing of Renal Replacement Therapy for Severe Acute Kidney Injury in Critica…
Acute kidney injury (AKI) affects many intensive care unit patients and is responsible for increased morbidity and mortality. Although life-saving in many situations, renal replacement therapy (RRT) may be associated with complications and the appropriate timing of its initiation is still the subject of intense debate. An early initiation strategy can prevent some metabolic complications where…
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Extrapulmonary involvement in pediatric tuberculosis
Tuberculosis in childhood is clinically challenging, but it is a preventable and treatable disease. Risk factors depend on age and immunity status. The most common form of pediatric tuberculosis is pulmonary disease, which comprises more than half of the cases. Other forms make up the extrapulmonary tuberculosis that involves infection of the lymph nodes, central nervous system, gastrointesti…
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