Heparin-induced thrombocytopenia (HIT) is an immune complication of heparin therapy caused by antibodies to complexes of platelet factor 4 (PF4) and heparin. Pathogenic antibodies to PF4/heparin bind and activate cellular FcγRIIA on platelets and monocytes to propagate a hypercoagulable state culminating in life-threatening thrombosis. It is now recognized that anti- PF4/heparin antibodies de…
The aim of this study was to develop the Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) to measure the functional problems that are most troublesome to patients with nocturnal allergic rhinoconjunctivitis (NAR).
There is limited information on contemporary incidence rates and trends, by race, ethnicity, and age, for major subtypes of esophageal and gastric cancer in the United States. We examined the most recent nationwide incidence data for esophageal squamous cell carcinoma, esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA), and gastric non-cardia adenocarcinoma (GNCA) by race, et…
Although swallowed topical corticosteroids (STCs) are effective in inducing remission of active eosinophilic esophagitis (EoE), there are few data on maintenance of long-term remission. We evaluated the long-term effectiveness of STC therapy for adults with EoE.
This study aims to develop a scoring system that will predict in-hospital morbidity post gastrointestinal (GI), pancreatic, hepatic cancer surgery in adult patients. This study took place in De La Salle University Medical Center
Atrial septal defect (ASD) closure is performed to prevent right ventricular (RV) dysfunction and pulmonary hypertension (PH). Persistent PH after ASD closure is associated with poor clinical outcome
Much of the decline in childhood mortality over the past two decades is attributable to improvements in neonatal intensive care for very-low-birthweight infants. Yet large and persistent disparities persist in the quality of neonatal intensive care across hospitals. Improving care for infants now served by hospitals with poor outcomes can greatly reduce infant mortality, particularly among mino…
To evaluate the factors associated with neonatal mortality in infant born with low birth weight. Method: Cross-sectional study that analyzed data from 771 live births with low birth weight (
As per WHO, about 25 millions of low weight babies are born annually and they are predisposed to a numbers of problems like hypoglycaemia, infection, hypothermia, respiratory problems etc. They need special nursing care. The present study described the various clinical characteristics and the morbidity pattern among these babies. The study was conducted over a period of two months at a medical …
A cute kidney injury (AKI) is a very common problem in critically ill patients. With the integration of consensus AKI definition criteria from Risk, Injury, Failure, Loss, End-Stage Kidney Disease (RIFLE), Acute Kidney Injury Network (AKIN), and, most recently Kidney Disease Improving Global Outcomes (KDIGO), AKI incidence in adult intensive care unit (ICU) settings has been reported to range b…