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EGFR-mutant Non-small Cell Lung Cancer Accompanied by Transient Asymptomatic …
A 69-year-old man with post-operative recurrence of lung adenocarcinoma was treated with multiple chemotherapies, including epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors. A second biopsy revealed an EGFR T790M mutation. As 10th-line chemotherapy, osimertinib was initiated. After 24 weeks, chest computed tomography (CT) revealed asymptomatic ground-glass opacities in both lo…
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Type 2 diabetes mellitus in children and adolescents
Type 2 diabetes mellitus is emerging as a new clinical problem within pediatric practice. Recent reports indicate an increasing prevalence of type 2 diabetes mellitus in children and adolescents around the world in all ethnicities, even if the prevalence of obesity is not increasing any more.
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Discovering biomedical semantic relations in PubMed queries for information r…
Identifying relevant papers from the literature is a common task in biocuration. Most current biomedical literature search systems primarily rely on matching user keywords. Semantic search, on the other hand, seeks to improve search accuracy by understanding the entities and contextual relations in user keywords
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Diagnosis and Classification of Diabetes Mellitus
Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels
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Personalized medicine in diabetes mellitus: current opportunities and future …
Diabetes mellitus affects approximately 382 million individuals worldwide and is a leading cause of morbidity and mortality. Over 40 and nearly 80 genetic loci influencing susceptibility to type 1 and type 2 diabetes, respectively, have been identified. Additionally, there is emerging evidence that some genetic variants help to predict response to treatment. Other variants confer apparent prote…
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Interactive Web-based regional journal club for postgraduate year 2 pharmacy …
Participation in journal club presentations has been repeatedly demonstrated to develop therapeutic knowledge, increase awareness of current research, and enhance critical thinking skills.1,2 However, literature evaluation activities may prove challenging for student pharmacists and residents. For pharmacy preceptors, initiating and maintaining a regular and effective journal club can be diffic…
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Procedure Logging in Interventional Cardiology Training Curriculum: The Inter…
Procedure logging is an integral part of the fellowship curriculum in cardiovascular medicine and its subspecialties, particularly for the cardiovascular disease fellows who are acquiring advanced training in interventional cardiology, structural heart diseases, or clinical cardiac electrophysiology.
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Remembering Kanu Chatterjee: A Gentle Giant of Cardiology
On March 4, 2015, Kanu Chatterjee, MBBS, a beloved physician, cardiologist, healer, teacher, and charismatic mentor, passed away peacefully in Iowa City, Iowa, after a brief battle with cancer. His passing has created an irretrievable loss for the field of cardiovascular medicine, because he was the essence of a clinician-teacher-investigator. Kanu was soft-spoken, kind, and wise; he was a pra…
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Hospitalist Career Decisions Among Internal Medicine Residents
Hospital medicine is a rapidly growing field of internal medicine. However, little is known about internal medicine residents’ decisions to pursue careers in hospital medicine (HM).
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Internal Medicine Point-of-Care Ultrasound Curriculum: Consensus Recommendati…
Bedside point-of-care ultrasound (POCUS) is increasingly used to assessmedical patients. At present, no consensus exists for what POCUS curriculum is appropriate for internal medicine residency training programs. This document details the consensus-based recommendations by the Canadian Internal Medicine Ultrasound (CIMUS) group, comprising 39 members, representing 14 institutions across Canada.
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