Erdosteine is a drug approved for the treatment of acute and chronic pulmonary diseases, originally developed as a mucolytic agent. It belongs to the thiol-based family of drugs that are known to also possess potentially important antioxidant and anti-inflammatory properties, and exhibit antibacterial activity against a variety of medically important bacterial species. Erdosteine is a prodru…
Erdosteine is a drug approved for the treatment of acute and chronic pulmonary diseases, originally developed as a mucolytic agent. It belongs to the thiol-based family of drugs that are known to also possess potentially important antioxidant and anti-inflammatory properties, and exhibit antibacterial activity against a variety of medically important bacterial species. Erdosteine is a prodru…
A previous meta-analysis suggested that the treatment with erdosteine was associated with significant amelioration of the cumulative global efficacy index and symptoms in comparison to placebo or other mucolytics. However, this conclusion was criticized because the meta-analysis, as it had been done, made it impossible to preclude the potential operation of selection biases within and across t…
COPD is incr easingly rec ognized as a le ading cause of morbidity and mortality thr oughout the world, and imposes a considerable bur den on he althcare resources. The goals of COPD management are currently to increase the time free of disease symptoms, to reduce the time spent in hospital and to improve exercise tolerance, health status and quality of life
Erdosteine, a drug approved for the treatment of acute and chronic pulmonary diseases, has been shownrnto be an effective treatment for chronic bronchitis or COPD (CB/COPD) in several studies, althoughrnmarked differences in the perception of its usefulness still remain.