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Found 2 from your keywords: author="Li C"
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EGFR T790M detection and osimertinib treatment response evaluation by liquid …
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Li C

Lung adenocarcinoma with EGFR activating mutations will inevitably acquire resistance to first generation TKIs. Acquired EGFR T790M mutation causes about 50% of these resistance cases. Droplet digital PCR ddPCR) and cobas enables quantification of T790M mutation. Whether these methods can predict clinical response of osimertinib treatment is unknown.

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Clinical Pharmacodynamics of Meropenem in Patients with Lower Respiratory Tra…
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Li C

Studies of  -lactam pharmacodynamics in infected patients are sparse. In this study, classification and regression tree (CART) and logistic regression analyses were used to identify which pharmacodynamic indices and magnitudes were significant predictors of meropenem efficacy for 101 adult patients with lower respiratory tract infections (LRTI). Using demographic data, a validated population p…

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