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Blackwell Publishing, Ltd. GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients


Progressive β-cell failure is a characteristic feature of type 2 diabetes; consequently, β-cell secretagogues are useful for achieving sufficient glycaemic control.
The European GUIDE study is the first large-scale head-to-head comparison of two sulphonylureas designed for once-daily administration used under conditions of everyday clinical practice


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English
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Eur J Clin Invest . 2004 Aug;34(8):535-42
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